{"id":"W2058990908","doi":"10.1016/j.jinorgbio.2005.04.021","title":"Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture","year":2005,"lang":"en","type":"article","venue":"Journal of Inorganic Biochemistry","topic":"Aluminum toxicity and tolerance in plants and animals","field":"Agricultural and Biological Sciences","cited_by":141,"is_retracted":false,"has_abstract":false,"ca_institutions":"Surrey Place Centre; University of Toronto","funders":"National Institute on Aging; National Institutes of Health","keywords":"Gene expression; Death-associated protein 6; Gene; Promoter; Chemistry; Molecular biology; Regulation of gene expression; Biology; Cell biology; Transcription factor; Cancer research; Biochemistry; Nuclear protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717646,0.0004893813,0.0005422836,0.0005338918,0.000462189,0.0004103784,0.0003244522,0.0002546364,0.005630976],"category_scores_gemma":[0.0001612268,0.0002734227,0.0006101915,0.000550482,0.0003097659,0.0002423678,0.0003196217,0.001147581,0.002160515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003931693,"about_ca_system_score_gemma":0.0005185303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003837779,"about_ca_topic_score_gemma":0.008644979,"domain_scores_codex":[0.9997063,0.00003858462,0.00002146841,0.00005810134,0.00006089334,0.0001146324],"domain_scores_gemma":[0.9997887,0.00007731656,0.00001563284,0.00002661828,0.00005888259,0.0000328828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000830968,0.0002155959,0.0003358955,0.0001702577,0.00002571635,0.0003386686,0.0001626083,0.00004274317,0.995088,0.0001097021,0.0006698972,0.002009821],"study_design_scores_gemma":[0.0001465454,0.001362017,0.01092951,0.00003458967,0.0001233666,0.001290966,0.0003565198,0.0004604147,0.9777298,0.0002317419,0.007319805,0.0000148501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9616929,0.01538652,0.008280568,0.0007194401,0.0004554256,0.0001771532,0.003169934,0.000170024,0.009947903],"genre_scores_gemma":[0.9536644,0.01110942,0.00625948,0.0003675174,0.0002259754,0.0003001792,0.007029972,0.00004816825,0.02099505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005630976,"threshold_uncertainty_score":0.01883745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009679426491618503,"score_gpt":0.2093319000156351,"score_spread":0.1996524735240166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}