{"id":"W2059039083","doi":"10.3390/genes5010051","title":"Lessons and Implications from Genome-Wide Association Studies (GWAS) Findings of Blood Cell Phenotypes","year":2014,"lang":"en","type":"article","venue":"Genes","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Doris Duke Charitable Foundation","keywords":"Genome-wide association study; Biology; Genetic association; Phenotype; Single-nucleotide polymorphism; Human genetics; Genetics; Computational biology; Genome; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002872259,0.00009458166,0.0001936072,0.00002571874,0.00008938063,0.000006695825,0.00009303448,0.0001325397,0.000006708965],"category_scores_gemma":[0.0007530696,0.00009095068,0.00004909912,0.00004689665,0.00004091914,0.000001936807,0.00009006682,0.00003542251,0.000005735211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000104553,"about_ca_system_score_gemma":0.00002045433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004338482,"about_ca_topic_score_gemma":0.00007614546,"domain_scores_codex":[0.9992681,0.00007435365,0.0002118357,0.000234484,0.00005210606,0.0001591877],"domain_scores_gemma":[0.9991916,0.0002755523,0.0001707288,0.000197576,0.0001289728,0.00003552304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000003252988,0.00003197921,0.7049537,0.000009911035,0.000176473,2.721369e-8,0.000101099,0.00007181084,0.2920754,0.00006488368,0.001563919,0.0009474889],"study_design_scores_gemma":[0.0003294843,0.00009284754,0.9260482,0.000003443668,0.0001495492,3.240388e-7,0.0001294658,0.00001212126,0.05537881,0.001991295,0.01573513,0.0001293794],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900334,0.006479533,0.00091807,0.00198415,0.00006471107,0.00007259576,0.00006462604,0.000006702625,0.0003761608],"genre_scores_gemma":[0.9932336,0.003107592,0.002509302,0.0003554229,0.000139695,0.00001528768,0.0001219279,0.00001013812,0.0005070582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2366966,"threshold_uncertainty_score":0.3708861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01650560692780359,"score_gpt":0.2677891484273743,"score_spread":0.2512835414995707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}