{"id":"W2059051998","doi":"10.1016/j.biopsych.2005.04.052","title":"Chronic Treatment with Mood Stabilizers Lithium and Valproate Prevents Excitotoxicity by Inhibiting Oxidative Stress in Rat Cerebral Cortical Cells","year":2005,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Excitotoxicity; Oxidative stress; Lithium (medication); Mood; Pharmacology; Valproic Acid; Cerebral cortex; Neuroscience; Medicine; Chemistry; Internal medicine; Glutamate receptor; Endocrinology; Psychology; Psychiatry; Receptor; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000896596,0.0003004478,0.0004021439,0.00004350002,0.00008455324,0.00001733428,0.00005289198,0.0001883794,0.00009295381],"category_scores_gemma":[0.000008482839,0.0001756253,0.00007652502,0.0001256284,0.000190539,0.00006397865,0.00003916116,0.0002516003,0.00001221262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002606618,"about_ca_system_score_gemma":0.0001118013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000608785,"about_ca_topic_score_gemma":0.0006518835,"domain_scores_codex":[0.9984375,0.0001375178,0.0003078524,0.0005489258,0.0001441504,0.0004240538],"domain_scores_gemma":[0.9994634,0.00005519947,0.000077211,0.0001696952,0.00001786882,0.0002166484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005619283,0.002944811,0.9681372,0.00005664999,0.0001313284,0.000004657905,0.000200799,0.000004633904,0.02099621,0.0000945108,0.00006129163,0.006805993],"study_design_scores_gemma":[0.03221819,0.0287293,0.7332336,0.0006232014,0.0003609115,0.00009002114,0.001567188,0.0003650557,0.1991134,0.0004497185,0.002164023,0.001085382],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991865,0.005173562,0.00004891443,0.001145855,0.00008125912,0.0009539176,0.00007040162,0.00005762337,0.0006034076],"genre_scores_gemma":[0.9975346,0.0003090251,0.001550413,0.00009579854,0.0001753519,0.00008921901,0.0000831142,0.00001685978,0.0001456183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2349036,"threshold_uncertainty_score":0.716179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01605666454915246,"score_gpt":0.2640180239737258,"score_spread":0.2479613594245733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}