{"id":"W2059055489","doi":"10.1073/pnas.0407577101","title":"Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; National Institutes of Health; National Eye Institute; York University; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Ludwig Institute for Cancer Research","keywords":"Cell biology; Ectoderm; Signal transduction; Receptor tyrosine kinase; Biology; Embryogenesis; Embryo","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008398747,0.0006321803,0.0001728812,0.0002148591,0.0002043381,0.0002033248,0.0001792712,0.0002823634,0.002643865],"category_scores_gemma":[0.0001049279,0.0001890042,0.0002955477,0.00009120523,0.0002429065,0.0001702486,0.0001621667,0.0003922404,0.000792569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003763538,"about_ca_system_score_gemma":0.0001641454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007914195,"about_ca_topic_score_gemma":0.00105389,"domain_scores_codex":[0.9999142,0.00000994634,0.000007838476,0.00002071314,0.00002171685,0.00002559236],"domain_scores_gemma":[0.9998922,0.000009315926,0.00004151663,0.000007700668,0.000007201358,0.00004213223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001774881,0.00001457291,0.0002936,0.00001553968,0.000004185328,0.0001438181,0.00000775676,0.00007386204,0.998541,0.00006998669,0.00003542896,0.0006227954],"study_design_scores_gemma":[0.0000850481,0.0002619149,0.04345568,0.0000165034,0.00002424495,0.001691553,0.00005211693,0.00144263,0.9488437,0.0001306838,0.003983911,0.00001208892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961239,0.0006950427,0.001650973,0.00006082113,0.00002968488,0.00002063191,0.0002972943,0.00005442973,0.001067325],"genre_scores_gemma":[0.9944124,0.0004835363,0.001019372,0.00003603326,0.00001986313,0.00002966433,0.0009644168,0.00001855099,0.003016146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002643865,"threshold_uncertainty_score":0.008844554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1315436801678228,"score_gpt":0.3862826746254003,"score_spread":0.2547389944575775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}