{"id":"W2059072558","doi":"10.2165/00003495-200464010-00003","title":"First-Line Treatment Strategies to Improve Survival in Patients with Advanced Colorectal Cancer","year":2004,"lang":"en","type":"review","venue":"Drugs","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Irinotecan; Colorectal cancer; Oxaliplatin; Oncology; Chemotherapy; Internal medicine; Disease; Cetuximab; Cancer; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000388216,0.0006629117,0.002186055,0.0001795133,0.00007986769,0.00002835768,0.00009005301,0.000141411,0.00005953899],"category_scores_gemma":[0.00001097358,0.000392185,0.0002500506,0.0004319735,0.00005417575,0.00006914197,0.00005653816,0.0001821777,0.00002476321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002996407,"about_ca_system_score_gemma":0.001098535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001477551,"about_ca_topic_score_gemma":0.005176632,"domain_scores_codex":[0.9981079,0.00002780441,0.0004394855,0.0006492572,0.0003269525,0.0004486576],"domain_scores_gemma":[0.9992274,0.00006770466,0.0001710357,0.0002574181,0.0001131105,0.0001633298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001007429,0.0008316142,0.001130363,0.004086567,0.0008136581,0.00004968605,0.0009152353,0.0000512345,7.006218e-8,0.0000216286,0.000009758727,0.9910827],"study_design_scores_gemma":[0.01389795,0.01464567,0.01212167,0.02435779,0.002639297,0.00000255209,0.0003933341,0.000001078075,0.000006174755,0.00001792463,0.930966,0.0009505787],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01862191,0.974371,0.000001566047,0.00009810929,0.0005497533,0.004228866,0.0004581255,0.00005811709,0.001612527],"genre_scores_gemma":[0.01018111,0.9861246,0.00009958298,0.00002248213,0.0001403618,0.002640104,0.0002544537,0.00007888591,0.0004584664],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9901322,"threshold_uncertainty_score":0.999853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01853248087047324,"score_gpt":0.325341864936809,"score_spread":0.3068093840663357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}