{"id":"W2059075557","doi":"10.1038/nrclinonc.2014.200","title":"Current treatment landscape for relapsed and/or refractory multiple myeloma","year":2014,"lang":"en","type":"review","venue":"Nature Reviews Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":198,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Pomalidomide; Medicine; Multiple myeloma; Carfilzomib; Refractory (planetary science); Lenalidomide; Bortezomib; Oncology; Internal medicine; Regimen; Ixazomib; Disease; Thalidomide; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009035217,0.0006947732,0.00182441,0.001838643,0.0002944898,0.001194085,0.0008859391,0.001203071,0.00435162],"category_scores_gemma":[0.001554171,0.0003126805,0.000705084,0.00170401,0.0005037313,0.001487713,0.000840782,0.002157297,0.001323266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008424127,"about_ca_system_score_gemma":0.001399562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001311607,"about_ca_topic_score_gemma":0.003802406,"domain_scores_codex":[0.9997076,0.00007118172,0.00005739348,0.00004651036,0.00008954494,0.00002772782],"domain_scores_gemma":[0.9994338,0.0003287694,0.00009866544,0.00001120071,0.00009556783,0.00003202959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009799835,0.0000392375,0.0001591341,0.01814646,0.0001080026,0.00009805658,0.00003941512,0.000258809,0.0004360064,0.00194478,0.03781139,0.9408605],"study_design_scores_gemma":[0.00007359975,0.0001364999,0.000847048,0.01170913,0.0004443415,0.000989571,0.00007564859,0.0001512297,0.0002087759,0.002540116,0.9828001,0.0000238224],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003412835,0.9990337,0.00004813915,0.000407488,0.0001213485,0.0000021896,0.000009659431,0.000004221096,0.0003392511],"genre_scores_gemma":[0.0005341591,0.9982995,0.0001257535,0.000556273,0.0002324256,0.000005423052,0.00001804385,0.000001168898,0.0002272527],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00435162,"threshold_uncertainty_score":0.0145576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2542302185574246,"score_gpt":0.5603429840524028,"score_spread":0.3061127654949782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}