{"id":"W2059154739","doi":"10.1016/j.biomaterials.2011.02.013","title":"The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides","year":2011,"lang":"en","type":"article","venue":"Biomaterials","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":385,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC; Advanced Foods and Materials Network","keywords":"Biofilm; Materials science; Biocompatibility; Antimicrobial; Coating; Implant; Conjugated system; In vivo; Antimicrobial peptides; Polymer; Biomedical engineering; Nanotechnology; Microbiology; Bacteria; Composite material; Biology; Medicine; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003213676,0.0003382857,0.0001519651,0.0001657025,0.0001156366,0.0002711308,0.0001559475,0.0003414104,0.0004776865],"category_scores_gemma":[0.0006870624,0.0002586394,0.0001676711,0.0001112344,0.0002769439,0.0003296875,0.0001887622,0.0003004281,0.0001019834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001568764,"about_ca_system_score_gemma":0.0001369474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002305551,"about_ca_topic_score_gemma":0.0003832395,"domain_scores_codex":[0.9998553,0.00002203507,0.00001118531,0.00002291346,0.00004698259,0.00004157789],"domain_scores_gemma":[0.9996763,0.0001247306,0.0000824985,0.00002885095,0.00005190299,0.00003566264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001149672,0.000009057722,0.0001067206,0.00002642692,0.000002763833,0.00001356196,0.00001622894,0.00002843822,0.9986743,0.00002592938,0.000008002497,0.0009735955],"study_design_scores_gemma":[0.00001039612,0.0002485821,0.002317317,0.000003444634,0.00001483769,0.00005296718,0.00001328382,0.0003653317,0.9966169,0.00001761292,0.0003351393,0.000004075438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979578,0.00110551,0.0005359851,0.00002131726,0.00001359809,0.000008979794,0.0000237958,0.000006067706,0.0003270043],"genre_scores_gemma":[0.997879,0.0005274486,0.0007873796,0.00002277458,0.000008779545,0.00001282348,0.00004295721,0.000007063685,0.0007116636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004776865,"threshold_uncertainty_score":0.001699626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01593837780132316,"score_gpt":0.209958392273827,"score_spread":0.1940200144725039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}