{"id":"W2059196682","doi":"10.1074/jbc.m005631200","title":"Functional Interplay between Type I Collagen and Cell Surface Matrix Metalloproteinase Activity","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research and Materiel Command; National Institutes of Health; National Cancer Institute; U.S. Army; National Institute of General Medical Sciences; Northwestern University","keywords":"Matrix metalloproteinase; Type I collagen; Metalloproteinase; Cell biology; Chemistry; Matrix (chemical analysis); Biophysics; Biochemistry; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001772607,0.0002326336,0.0001671504,0.000186648,0.00009743143,0.0005025034,0.0001623222,0.0002592301,0.001362198],"category_scores_gemma":[0.0002098199,0.0001459082,0.0002002499,0.0001849667,0.0001492659,0.0001952872,0.0001189397,0.0002486572,0.0004718204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003581595,"about_ca_system_score_gemma":0.0001886173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006177347,"about_ca_topic_score_gemma":0.0008501383,"domain_scores_codex":[0.9997417,0.00005203157,0.00001789913,0.00003539414,0.00006123847,0.00009175806],"domain_scores_gemma":[0.9996949,0.00009565682,0.00004975586,0.0000281352,0.00004629607,0.00008522194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001213816,0.000009973123,0.0007130816,0.00002595238,0.000004274539,0.00004315514,0.000007283152,0.00001041463,0.9982418,0.00004452099,0.00001784588,0.0007604244],"study_design_scores_gemma":[0.00002194901,0.0002993971,0.05677898,0.00001129517,0.0000310864,0.0008920615,0.00007624892,0.0007100116,0.9385115,0.00006684199,0.002594792,0.000005916941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919509,0.004217676,0.001317111,0.00008817191,0.00002295627,0.00001698459,0.0003409572,0.00002481516,0.00202037],"genre_scores_gemma":[0.9956297,0.0009655656,0.000932148,0.00004479478,0.00001682108,0.0000199352,0.0006084545,0.000008914382,0.001773649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001362198,"threshold_uncertainty_score":0.004557014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02055155991123617,"score_gpt":0.2709672955188454,"score_spread":0.2504157356076092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}