{"id":"W2059287676","doi":"10.1158/0008-5472.can-10-1513","title":"Tumor Cell Invasion Is Promoted by Interstitial Flow-Induced Matrix Priming by Stromal Fibroblasts","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Oncosuisse; Whitaker International Fellows and Scholars Program","keywords":"Fibroblast; Stromal cell; Cancer-Associated Fibroblasts; Tumor microenvironment; Cell biology; Chemistry; Cancer research; Extracellular matrix; Cell; Pathology; Biology; Medicine; Tumor cells; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010062,0.0002747335,0.0001268264,0.000158078,0.0001285579,0.0001965787,0.00006106088,0.0001325758,0.0007143874],"category_scores_gemma":[0.00009368218,0.0001242186,0.0001734151,0.00006793668,0.0001339241,0.0001417866,0.0001429542,0.0002483359,0.0001507533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00012661,"about_ca_system_score_gemma":0.0001417136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004000796,"about_ca_topic_score_gemma":0.0005080533,"domain_scores_codex":[0.9999223,0.00002121234,0.000003713691,0.00001199858,0.000016398,0.00002434478],"domain_scores_gemma":[0.9999493,0.00001197664,0.00001375164,0.000004708132,0.000004874866,0.00001534897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004986533,0.0000122208,0.0001914926,0.00001171715,0.000001177781,0.00005362743,0.00001004405,0.00002918374,0.9988426,0.00005761131,0.00001691837,0.000723412],"study_design_scores_gemma":[0.00003372457,0.0003504606,0.01707887,0.00000669547,0.00001413652,0.0004756206,0.00005963659,0.002916765,0.9771298,0.0001342641,0.001792146,0.00000787446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954854,0.000645298,0.002487042,0.00005272159,0.00001478057,0.0000141638,0.00005303773,0.00004484269,0.001202743],"genre_scores_gemma":[0.9975713,0.0003479884,0.001387748,0.00002155305,0.000008096444,0.00002066622,0.00005542199,0.000004946392,0.0005822678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007143874,"threshold_uncertainty_score":0.002389848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06158914105995587,"score_gpt":0.3507503020176765,"score_spread":0.2891611609577206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}