{"id":"W2059289294","doi":"10.1002/dvg.20727","title":"A phenotype‐driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development","year":2011,"lang":"en","type":"article","venue":"genesis","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Dental and Craniofacial Research; Stowers Institute for Medical Research","keywords":"Neural crest; Biology; Ectoderm; Craniofacial; Cell biology; Morphogenesis; Mesoderm; Endoderm; Cranial neural crest; Neural tube; Germ layer; Phenotype; Population; Genetics; Anatomy; Cellular differentiation; Embryonic stem cell; Embryogenesis; Embryo; Induced pluripotent stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001936701,0.0007534795,0.0002667918,0.0007818685,0.000192124,0.0001899574,0.0003589705,0.0003930626,0.001268947],"category_scores_gemma":[0.0001785054,0.000257984,0.0002437929,0.0002133429,0.000261918,0.00008627912,0.0002504436,0.0002630356,0.0003629324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001672295,"about_ca_system_score_gemma":0.0001618582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006067702,"about_ca_topic_score_gemma":0.001824328,"domain_scores_codex":[0.9997556,0.00004380334,0.00003363247,0.0000518507,0.00007581709,0.00003932221],"domain_scores_gemma":[0.9998206,0.00004983933,0.00005802188,0.00001517725,0.00001255658,0.0000437593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004339492,0.00003376955,0.0003922187,0.00001805287,0.000008715165,0.0002372132,0.00001217812,0.00008203158,0.9976557,0.00008387645,0.00002950032,0.001403289],"study_design_scores_gemma":[0.00002679313,0.0004040122,0.02015752,0.00001429477,0.00007765035,0.002623832,0.00003641496,0.002671047,0.9708685,0.00005890928,0.003045555,0.00001538023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853213,0.0004852271,0.01173259,0.00004780696,0.00001518374,0.00008911276,0.0006274767,0.0002908702,0.001390519],"genre_scores_gemma":[0.9813544,0.0006439214,0.01307356,0.00007073607,0.000008618198,0.00009650144,0.001346897,0.0001148666,0.003290465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001268947,"threshold_uncertainty_score":0.004245043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01797712424594987,"score_gpt":0.1991253641100032,"score_spread":0.1811482398640533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}