{"id":"W2059378639","doi":"10.1016/j.ultras.2010.01.009","title":"Microbubble mediated sonoporation of cells in suspension: Clonogenic viability and influence of molecular size on uptake","year":2010,"lang":"en","type":"article","venue":"Ultrasonics","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":114,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Health Sciences Centre; Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Sonoporation; Propidium iodide; Clonogenic assay; Biophysics; Intracellular; Viability assay; Flow cytometry; Permeability (electromagnetism); Materials science; Chemistry; Cell; Molecular biology; Ultrasound; Biochemistry; Microbubbles; Biology; Medicine; Apoptosis; Membrane; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001404358,0.00009419983,0.0001576875,0.00003778224,0.00001472189,0.000006501239,0.00008799337,0.0001083222,0.00002465118],"category_scores_gemma":[0.0001480393,0.00009585639,0.00002818235,0.0001768532,0.00006915085,0.00005286798,0.000007361614,0.0001792291,0.000005454221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001328667,"about_ca_system_score_gemma":0.00002729926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003030464,"about_ca_topic_score_gemma":0.0001707313,"domain_scores_codex":[0.9994011,0.00001168524,0.0002592829,0.0001310153,0.00008335554,0.000113551],"domain_scores_gemma":[0.9993361,0.0002687441,0.00004797256,0.0002469186,0.00006003302,0.00004021931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004986993,0.00004681904,0.001595528,0.00003427475,0.000006771382,3.587454e-7,0.0001708297,0.01075474,0.9867427,0.000349352,0.000008189969,0.0002854065],"study_design_scores_gemma":[0.0002861783,0.0000311716,0.03779094,0.00001559476,0.00001107537,0.000002450399,0.0000372923,0.001482646,0.9589573,0.0003884353,0.0008871675,0.0001097219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99933,0.00005942801,0.00006890758,0.00002886551,0.00003703124,0.0001800584,0.00002985536,0.0000318692,0.0002339719],"genre_scores_gemma":[0.9980395,0.00008024435,0.001819575,0.00001771404,0.000005968877,0.000008758266,0.000009463242,0.00001361264,0.000005142431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0361954,"threshold_uncertainty_score":0.390891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00356264939743019,"score_gpt":0.189778628881238,"score_spread":0.1862159794838078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}