{"id":"W2059394109","doi":"10.1016/j.ydbio.2015.03.020","title":"Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression","year":2015,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Homeobox; Zebrafish; Cell cycle; Cell biology; Neurogenesis; Gene knockdown; Embryonic stem cell; Progenitor cell; Cell division; Genetics; Cell; Gene; Gene expression; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002122386,0.0003225078,0.0003139527,0.0002540396,0.0003701092,0.0007391129,0.0003380066,0.000224745,0.001854459],"category_scores_gemma":[0.0002102643,0.0002659558,0.000207405,0.0001132701,0.0003204776,0.0003449699,0.0009807495,0.0006757556,0.0003567903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005752312,"about_ca_system_score_gemma":0.0003991347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005791155,"about_ca_topic_score_gemma":0.00211138,"domain_scores_codex":[0.9996672,0.00004781237,0.00002169044,0.00007039011,0.00009680016,0.00009617151],"domain_scores_gemma":[0.9998135,0.00002707167,0.00005263202,0.00001637345,0.00002195381,0.00006851501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007853801,0.000006312744,0.0005687983,0.00001099501,0.000003375438,0.00002983928,0.00001006935,0.00004684779,0.9981786,0.0004221822,0.00003343383,0.0006110829],"study_design_scores_gemma":[0.00001901027,0.00007495032,0.02038143,0.000006034031,0.00001407253,0.0002632169,0.00009843722,0.003031552,0.9736875,0.0002245787,0.002192582,0.000006635612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991989,0.001284805,0.002775327,0.0001102796,0.00002984646,0.00000756058,0.0001199059,0.00005928544,0.003624033],"genre_scores_gemma":[0.9951344,0.0001794598,0.0009204321,0.00004720213,0.000006414529,0.0000104387,0.0001563382,0.00002589531,0.003519372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001854459,"threshold_uncertainty_score":0.006203771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01150125521361391,"score_gpt":0.2235709884141315,"score_spread":0.2120697332005176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}