{"id":"W2059394109","doi":"10.1016/j.ydbio.2015.03.020","title":"Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression","year":2015,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Homeobox; Zebrafish; Cell cycle; Cell biology; Neurogenesis; Gene knockdown; Embryonic stem cell; Progenitor cell; Cell division; Genetics; Cell; Gene; Gene expression; Stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001717982,0.000189854,0.0002171903,0.00006250361,0.00006714596,0.000006110217,0.0002446343,0.0002062433,0.00001381347],"category_scores_gemma":[0.00005852905,0.000135305,0.0000566678,0.0001596662,0.0003322208,0.000005590885,0.0003553963,0.00006315567,0.000004761164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001318079,"about_ca_system_score_gemma":0.0002242526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003114646,"about_ca_topic_score_gemma":0.000009452396,"domain_scores_codex":[0.9988756,0.00009909194,0.0003381772,0.0003247877,0.0001266018,0.0002358116],"domain_scores_gemma":[0.9994119,0.00001378048,0.0001872043,0.0001897353,0.0001104966,0.00008691486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002581903,0.00006539829,0.1670285,0.00002493495,0.00002568861,8.304419e-7,0.0002367525,0.000001173688,0.8289425,0.00001666328,0.00141733,0.00198203],"study_design_scores_gemma":[0.0007608162,0.0003011858,0.01606783,0.00001943166,0.00001113976,0.0000258154,0.0006460709,0.000003283001,0.9715304,0.0001712542,0.01027594,0.0001868706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965851,0.001654636,0.00001590395,0.00006697697,0.0002545139,0.0002152449,0.00001954001,0.000008567818,0.001179563],"genre_scores_gemma":[0.9959357,0.0003846848,0.002997312,0.0000452927,0.00004885589,0.00001131414,0.0002029392,0.0000156758,0.0003581724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1509606,"threshold_uncertainty_score":0.5517577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01150125521361391,"score_gpt":0.2235709884141315,"score_spread":0.2120697332005176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}