{"id":"W2059601988","doi":"10.4161/cc.21789","title":"Independent transcriptional reprogramming and apoptosis induction by cisplatin","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Cisplatin; Cell biology; DNA damage; Ceramide; Programmed cell death; Apoptosis; Biology; Reprogramming; Signal transduction; Clonogenic assay; Chemistry; Cancer research; Cell; Genetics; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000151482,0.00007930928,0.00005522214,0.00001559866,0.00005549045,0.0000147526,0.00004659012,0.000112597,0.00003374449],"category_scores_gemma":[0.000008116654,0.00008300624,0.00003359903,0.00002987803,0.00002295496,0.000007289027,0.0000318491,0.00005936511,0.00001051505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008724973,"about_ca_system_score_gemma":0.000007130774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001155333,"about_ca_topic_score_gemma":0.000001305352,"domain_scores_codex":[0.9994187,0.00002407438,0.00009263533,0.0001919996,0.00009075905,0.0001818457],"domain_scores_gemma":[0.999725,0.000002500316,0.00003262646,0.0001394312,0.0000147369,0.00008567212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001159731,0.00006623627,0.00199296,0.000008283442,0.000008234527,7.196736e-8,0.00006960087,0.000001887252,0.9916747,0.00008314552,0.0005369609,0.005546372],"study_design_scores_gemma":[0.0002441658,0.00006700688,0.001522716,0.000002291102,0.0000118478,0.000007798988,0.0001198141,0.00001525066,0.9790586,0.00007659047,0.01876488,0.0001089838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995298,0.0009699877,0.00219302,0.0000316959,0.000189249,0.00009193185,0.000005502364,0.00001653119,0.00120404],"genre_scores_gemma":[0.9965998,0.00003617051,0.002335871,0.00006455161,0.0001505553,0.00001923884,0.00007511196,0.00001427995,0.000704413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01822792,"threshold_uncertainty_score":0.3384896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008200036610524746,"score_gpt":0.2197443764863467,"score_spread":0.211544339875822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}