{"id":"W2059601988","doi":"10.4161/cc.21789","title":"Independent transcriptional reprogramming and apoptosis induction by cisplatin","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Cisplatin; Cell biology; DNA damage; Ceramide; Programmed cell death; Apoptosis; Biology; Reprogramming; Signal transduction; Clonogenic assay; Chemistry; Cancer research; Cell; Genetics; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001195181,0.0002487297,0.0002262244,0.0002048439,0.0001233963,0.0003495329,0.0001815223,0.0002050239,0.001631845],"category_scores_gemma":[0.0002028475,0.0001130369,0.0002341706,0.0001362661,0.0002930561,0.0002107253,0.0003913064,0.0004519633,0.0004079817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003066916,"about_ca_system_score_gemma":0.0002154669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002429811,"about_ca_topic_score_gemma":0.0004365368,"domain_scores_codex":[0.9997724,0.00003227302,0.00001880933,0.00005783159,0.00008087457,0.0000378217],"domain_scores_gemma":[0.9998584,0.00003013024,0.00003490931,0.00002723743,0.00002715281,0.00002217076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004270788,0.000009375426,0.0001637062,0.00001718886,0.000001415086,0.00002538124,0.000007825576,0.00003858932,0.9990476,0.0001027142,0.00001263405,0.0005308681],"study_design_scores_gemma":[0.000005998523,0.0001185079,0.00751602,0.000003458975,0.000007226179,0.0001682522,0.00003535878,0.0006672234,0.9898287,0.00009015646,0.001555212,0.000003819462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878395,0.002105216,0.00541807,0.0001423783,0.00003727752,0.00005178981,0.0009215932,0.00009601513,0.003388237],"genre_scores_gemma":[0.995027,0.0007773043,0.001082891,0.0000671001,0.000008634836,0.00004847857,0.000924465,0.0000155561,0.002048508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001631845,"threshold_uncertainty_score":0.00545913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008200036610524746,"score_gpt":0.2197443764863467,"score_spread":0.211544339875822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}