{"id":"W2059757881","doi":"10.1128/aac.00564-13","title":"Determination of <i>In Vitro</i> Activities of Solithromycin at Different pHs and Its Intracellular Activity against Clinical Isolates of Neisseria gonorrhoeae from a Laboratory Collection","year":2013,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of Toronto; Public Health Ontario; Toronto Public Health","funders":"","keywords":"Azithromycin; Ketolide; Microbiology; Neisseria gonorrhoeae; Minimum inhibitory concentration; Biology; Potency; In vitro; Antibiotics; Antibacterial agent","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001659333,0.0001510042,0.0004630958,0.0001270336,0.00006599165,0.000008839276,0.00007144175,0.0002065764,0.0001469955],"category_scores_gemma":[0.00003605315,0.0001339675,0.00006480548,0.0001321725,0.0002930371,0.0001770524,0.00005548418,0.0001806002,0.000003101856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003508253,"about_ca_system_score_gemma":0.00002985789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004634601,"about_ca_topic_score_gemma":0.00003953661,"domain_scores_codex":[0.998883,0.0002441802,0.0003896221,0.000294097,0.00002004895,0.0001690282],"domain_scores_gemma":[0.9992453,0.0001741391,0.000280374,0.0001630851,0.0001180791,0.00001902063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006246388,0.0006607241,0.05288697,0.00006619509,0.0001171509,1.257518e-7,0.0004599812,5.183712e-7,0.933371,0.000002002616,0.0001596685,0.01165103],"study_design_scores_gemma":[0.001254,0.0001556028,0.2596717,0.00003415214,0.00001234499,0.000001916376,0.00005240933,0.00007448591,0.7385123,0.00001279731,0.0001390468,0.00007925736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988869,0.0002407369,0.00003181641,0.0001609161,0.0001495585,0.0004226705,0.00007325826,0.000008512503,0.00002563452],"genre_scores_gemma":[0.997184,0.002516956,0.00005403405,0.00004782934,0.00001654059,0.00001147673,0.00002671464,0.00001449788,0.0001279802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2067848,"threshold_uncertainty_score":0.5463035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01552238986136923,"score_gpt":0.2790408425616244,"score_spread":0.2635184527002552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}