{"id":"W2059775920","doi":"10.1136/gut.2003.035253","title":"CDP571, a humanised monoclonal antibody to tumour necrosis factor α, for moderate to severe Crohn’s disease: a randomised, double blind, placebo controlled trial","year":2004,"lang":"en","type":"article","venue":"Gut","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Western University","funders":"","keywords":"Medicine; Placebo; Internal medicine; Crohn's disease; Gastroenterology; Clinical trial; Adverse effect; Placebo-controlled study; Disease; Surgery; Double blind; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002373817,0.0003950438,0.0005018837,0.0001013312,0.000264581,0.0001667655,0.0003379143,0.0001630298,0.00008193067],"category_scores_gemma":[0.0002619674,0.0003724035,0.0005159591,0.00007888459,0.000037243,0.00001242415,0.0001289235,0.00008624011,0.00009722122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007544403,"about_ca_system_score_gemma":0.0006092729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001768038,"about_ca_topic_score_gemma":0.00006963477,"domain_scores_codex":[0.9978551,0.00007224209,0.0004992021,0.000715784,0.0002676759,0.0005899824],"domain_scores_gemma":[0.9983876,0.00003058975,0.0001320019,0.0004992026,0.0002293554,0.0007212254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8665758,0.0002221457,0.00003249538,0.00003557204,0.000172682,0.00007697851,0.0001097568,0.005515797,0.1262314,0.00009902183,0.0008891029,0.00003923167],"study_design_scores_gemma":[0.98392,0.000414812,0.002256259,0.00003081679,0.0001637517,0.000002843606,0.000019679,0.0001915414,0.01033169,0.0001784681,0.001877718,0.0006123543],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815615,0.00006109195,0.005262123,0.0003862769,0.0003740312,0.0114714,0.0005740324,0.00005014459,0.0002593602],"genre_scores_gemma":[0.9909551,0.000005635213,0.0008808218,0.001032754,0.000748259,0.003946663,0.000324919,0.00007509085,0.002030748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1173443,"threshold_uncertainty_score":0.9998728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01988479544663712,"score_gpt":0.2962970440908733,"score_spread":0.2764122486442361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}