{"id":"W2059801006","doi":"10.1371/journal.ppat.1000101","title":"Lysis of Endogenously Infected CD4+ T Cell Blasts by rIL-2 Activated Autologous Natural Killer Cells from HIV-Infected Viremic Individuals","year":2008,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Cytolysis; NK-92; NKG2D; Natural killer T cell; Heterologous; Interleukin 21; T cell; Immunology; Natural killer cell; Major histocompatibility complex; Cytotoxic T cell; Antigen; Virology; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009117348,0.0004463617,0.0007126826,0.0003101666,0.0003352872,0.00001381534,0.0002844472,0.00059985,0.00389462],"category_scores_gemma":[0.0001460851,0.0004180162,0.0002956582,0.0004354677,0.000239933,0.0001968002,0.0001210745,0.0007464314,0.002132128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001201637,"about_ca_system_score_gemma":0.000103844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002793679,"about_ca_topic_score_gemma":0.00001042421,"domain_scores_codex":[0.9974668,0.000539878,0.0007136539,0.0005726588,0.0001206771,0.0005863442],"domain_scores_gemma":[0.9982857,0.0003350406,0.0005326621,0.0005239904,0.0002704145,0.00005223737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000227277,0.0008662261,0.005905139,0.00001482909,0.0005484201,0.00001614052,0.001270799,0.0000148843,0.9578761,0.000001175452,0.03300562,0.0002533375],"study_design_scores_gemma":[0.002003841,0.000260622,0.0105469,0.00003361498,0.0002576587,0.00007128713,0.0001345454,0.00003881892,0.9687175,0.000003181949,0.01752092,0.0004110973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934179,0.001173103,0.00008245515,0.00003601857,0.003469173,0.0004057028,0.0002672936,0.0003300628,0.0008183569],"genre_scores_gemma":[0.9886127,0.0002945057,0.0001152554,0.0001699305,0.00004348654,0.00003061909,0.003099603,0.00005926448,0.007574606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0154847,"threshold_uncertainty_score":0.9998271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009657913843050927,"score_gpt":0.191522014507341,"score_spread":0.1818641006642901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}