{"id":"W2059842692","doi":"10.1016/j.bpj.2012.08.060","title":"STICCS Reveals Matrix-Dependent Adhesion Slipping and Gripping in Migrating Cells","year":2012,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institutes of Health; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Ministerio de Ciencia e Innovación; Ministerio de Economía y Competitividad","keywords":"Integrin; Paxillin; Adhesion; Biophysics; Focal adhesion; Chemistry; Fluorescence correlation spectroscopy; Total internal reflection fluorescence microscope; Cell biology; Membrane; Biochemistry; Biology; Molecule; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026358,0.0001725158,0.0002270161,0.0003127303,0.0002999782,0.0004845197,0.0002950525,0.00040658,0.001758089],"category_scores_gemma":[0.000235141,0.0002138676,0.0002315778,0.000188209,0.0002739512,0.0002225171,0.0003037526,0.0006922669,0.0005167267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004616208,"about_ca_system_score_gemma":0.0002124356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001013918,"about_ca_topic_score_gemma":0.001892007,"domain_scores_codex":[0.9998614,0.00000879551,0.000008866768,0.00002380311,0.00005955777,0.00003759204],"domain_scores_gemma":[0.9997267,0.00005475532,0.00006645986,0.00004399801,0.00003472138,0.00007329028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006717496,0.00000810034,0.0002837947,0.00001370559,0.000003979892,0.0001065772,0.00001830623,0.00008376236,0.9979876,0.000186229,0.00006824987,0.001172479],"study_design_scores_gemma":[0.00001442694,0.00005313105,0.01314964,0.000005711864,0.000009702541,0.0003311002,0.00004706481,0.004455627,0.9807786,0.0001109832,0.001034397,0.000009647071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963541,0.0002468925,0.002198437,0.00007467002,0.00002333965,0.00000671307,0.0001892468,0.00005227673,0.0008542463],"genre_scores_gemma":[0.9959428,0.000163555,0.001195482,0.00005549888,0.00001203082,0.00001574887,0.0002787565,0.00003829724,0.002297899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001758089,"threshold_uncertainty_score":0.005881429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009805388512621716,"score_gpt":0.2894680288957626,"score_spread":0.2796626403831409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}