{"id":"W2059896966","doi":"10.1016/j.mad.2007.05.001","title":"Lower GrB+ CD62Lhigh CD8 TCM effector lymphocyte response to influenza virus in older adults is associated with increased CD28null CD8 T lymphocytes","year":2007,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; NIH Clinical Center; National Institutes of Health","keywords":"CTL*; Cytotoxic T cell; CD8; Immunology; Peripheral blood mononuclear cell; Virus; CD28; Virology; Biology; Immune system; Immunosenescence; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001956945,0.0003583193,0.0004526747,0.0006688757,0.000259668,0.0003470826,0.0002086713,0.0005022977,0.002593872],"category_scores_gemma":[0.0005325648,0.0002896332,0.0002183199,0.0002720166,0.0002042316,0.0002385979,0.0002649664,0.0004766953,0.0003763402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008881866,"about_ca_system_score_gemma":0.00006855238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006657676,"about_ca_topic_score_gemma":0.0006994918,"domain_scores_codex":[0.9998896,0.0000166206,0.00001528407,0.00003661298,0.00001788135,0.00002405045],"domain_scores_gemma":[0.9994715,0.00005364037,0.0002372591,0.00004808407,0.00005822213,0.0001312675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006571284,0.000258667,0.5861085,0.0001418965,0.0001393206,0.001663444,0.0004028341,0.0001005508,0.3909257,0.00006581378,0.0003910509,0.01323089],"study_design_scores_gemma":[0.00001496722,0.0004355484,0.9932644,0.000004721866,0.00004050756,0.001395909,0.0001119064,0.0001347273,0.004325302,0.00004333361,0.0002235631,0.000005098616],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999383,0.0001440416,0.0001481451,0.00001664525,0.000006008896,0.000002210092,0.00008306187,0.000009652713,0.0002072862],"genre_scores_gemma":[0.9987943,0.00006715595,0.0001610479,0.00002915674,0.00001983847,0.000007030259,0.0001332162,0.000006644687,0.0007815718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002593872,"threshold_uncertainty_score":0.008677363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006856613762209833,"score_gpt":0.218106540803032,"score_spread":0.2112499270408222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}