{"id":"W2059922747","doi":"10.1016/j.biochi.2008.02.015","title":"Identification of ETA and ETB binding domains using ET-derived photoprobes","year":2008,"lang":"eu","type":"article","venue":"Biochimie","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Receptor; Stereochemistry; Chemistry; Peptide; Transfection; Residue (chemistry); Binding site; G protein-coupled receptor; Ligand (biochemistry); Biochemistry; Molecular biology; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002853345,0.0002671864,0.000220073,0.0002295796,0.0002951588,0.0004008271,0.0004532166,0.000758866,0.002586565],"category_scores_gemma":[0.0004232137,0.0002785776,0.0002610385,0.0002224335,0.0003211284,0.0004581652,0.0003614103,0.001239521,0.0008568522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006068691,"about_ca_system_score_gemma":0.000215584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008047528,"about_ca_topic_score_gemma":0.001038473,"domain_scores_codex":[0.9998883,0.00002213033,0.000004926153,0.00003014608,0.00002115289,0.00003337383],"domain_scores_gemma":[0.9997318,0.0001339255,0.00002652524,0.00002668079,0.00002307609,0.00005780725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001153846,0.00001145252,0.00005547028,0.00001574481,0.000001960904,0.00002956359,0.0000144404,0.00007296266,0.9986367,0.0004400555,0.00004073756,0.0005657113],"study_design_scores_gemma":[0.00001891578,0.0000375046,0.00109003,0.000003375981,0.000003078762,0.0001556166,0.00002204134,0.001176231,0.9950274,0.0002071561,0.002253324,0.000005431288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9504049,0.001488521,0.0434323,0.0005635536,0.00006133314,0.00005804635,0.0007299967,0.0001345508,0.003126857],"genre_scores_gemma":[0.959021,0.00102568,0.02772166,0.0003533524,0.00002777612,0.0001545593,0.001824381,0.00007972633,0.0097919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002586565,"threshold_uncertainty_score":0.008652925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02570203237546684,"score_gpt":0.2664141078218429,"score_spread":0.240712075446376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}