{"id":"W2059922747","doi":"10.1016/j.biochi.2008.02.015","title":"Identification of ETA and ETB binding domains using ET-derived photoprobes","year":2008,"lang":"eu","type":"article","venue":"Biochimie","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Receptor; Stereochemistry; Chemistry; Peptide; Transfection; Residue (chemistry); Binding site; G protein-coupled receptor; Ligand (biochemistry); Biochemistry; Molecular biology; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003147648,0.0002150168,0.0002481948,0.00008721104,0.0002068894,0.00003448984,0.0001429431,0.0002614102,0.00005545655],"category_scores_gemma":[0.00005624611,0.000218809,0.0001180035,0.0001083833,0.000164211,0.00000993388,0.0001277027,0.00009924795,0.000003126147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001392098,"about_ca_system_score_gemma":0.0001125172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004568719,"about_ca_topic_score_gemma":0.000005920496,"domain_scores_codex":[0.9986248,0.00009898206,0.0004320753,0.0004327867,0.0001678524,0.0002435036],"domain_scores_gemma":[0.9991981,0.00001463845,0.0003061719,0.000301633,0.00009034565,0.00008909588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003796286,0.00006186296,0.0004573159,0.00007123109,0.00007946722,0.000003862615,0.0002621702,0.0001275554,0.9984591,0.0002010893,0.00005658563,0.0001818147],"study_design_scores_gemma":[0.0004598655,0.0001276286,0.0003127839,0.00005659062,0.00005591598,0.00004118141,0.000185903,0.001393704,0.9967493,0.00005455206,0.0003183082,0.000244207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860306,0.002716795,0.01048472,0.00005939697,0.0003087725,0.0002286175,0.0000590403,0.00000870814,0.0001033441],"genre_scores_gemma":[0.9933871,0.002451061,0.00363789,0.00007695981,0.0001334321,0.00000495944,0.00006232778,0.0000344318,0.0002118167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007356519,"threshold_uncertainty_score":0.8922772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02570203237546684,"score_gpt":0.2664141078218429,"score_spread":0.240712075446376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}