{"id":"W2059939522","doi":"10.1186/ar3964","title":"Dysregulation of the serine/threonine phosphatase PP2A contributes to autoimmunity","year":2012,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Canadian Arthritis Network; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Arthritis Society; Lupus Research Alliance; Arthritis Foundation","keywords":"Protein phosphatase 2; Immune system; Immunology; Autoimmunity; Lupus nephritis; Glomerulonephritis; Biology; Immune dysregulation; FOXP3; Phosphatase; Endocrinology; Internal medicine; Medicine; Cell biology; Kidney; Phosphorylation; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003412869,0.0008242339,0.0004760941,0.0005416442,0.0003005275,0.001072236,0.0003017935,0.000493489,0.001891399],"category_scores_gemma":[0.0003751205,0.0002966119,0.0004075273,0.0003642496,0.0005222273,0.0003018156,0.0006241427,0.0009869867,0.001041518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004390232,"about_ca_system_score_gemma":0.0004336693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004933171,"about_ca_topic_score_gemma":0.0003825334,"domain_scores_codex":[0.9995708,0.00007140121,0.00003915696,0.0001367281,0.0001202653,0.00006168092],"domain_scores_gemma":[0.9997076,0.00002385835,0.0001105655,0.00003286452,0.00004115959,0.00008388639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001105619,0.0001758633,0.01931184,0.001199037,0.0002978006,0.003077456,0.0001097407,0.0009270427,0.8981168,0.002953033,0.005106143,0.06761966],"study_design_scores_gemma":[0.0003053644,0.00134009,0.2846734,0.0003006186,0.00106749,0.02414859,0.0003752463,0.006206092,0.4306492,0.01189078,0.2389299,0.0001133444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7090731,0.2294491,0.02348651,0.003384219,0.001246807,0.0001113704,0.001680584,0.001811496,0.02975686],"genre_scores_gemma":[0.9563899,0.0346854,0.001804851,0.0003663487,0.0003302811,0.00005208833,0.0003901392,0.00006673009,0.005914155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001891399,"threshold_uncertainty_score":0.006327391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03493417959709986,"score_gpt":0.3059211735971714,"score_spread":0.2709869940000715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}