{"id":"W2059955786","doi":"10.1038/sj.gt.3302682","title":"RNAi therapeutics: Can siRNAs conquer SARS?","year":2005,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Small interfering RNA; Biology; Virology; RNA interference; Intensive care medicine; Medicine; RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009545521,0.0001792245,0.0001289869,0.00003292461,0.00006962407,0.000029611,0.0002598234,0.0001325939,0.0001479167],"category_scores_gemma":[0.000002770692,0.0001550895,0.0001032544,0.00004801589,0.00006159948,0.000003617657,0.00003733215,0.00007735756,0.0001138689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001538618,"about_ca_system_score_gemma":0.00006217488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003680784,"about_ca_topic_score_gemma":0.00008281405,"domain_scores_codex":[0.9990979,0.00004494622,0.0001703905,0.0003002051,0.0001078773,0.0002787022],"domain_scores_gemma":[0.9993836,0.000004295585,0.00005442376,0.0004168586,0.00008068972,0.00006017481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001117071,0.00005271172,0.0005511036,9.334866e-7,0.0001136412,0.000001673518,0.0001254608,0.00003901231,0.9306492,0.00001927005,0.003750679,0.06458456],"study_design_scores_gemma":[0.0005033892,0.0002740428,0.0007607689,0.00000231181,0.000005572857,0.00001259251,0.00002609909,0.00002051108,0.7184302,0.00005450717,0.2797425,0.000167522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919592,0.004584527,0.0003248194,0.001151822,0.0001851075,0.0001306248,0.00001862958,0.00002222701,0.001623094],"genre_scores_gemma":[0.9808381,0.006125923,0.0004844038,0.008825749,0.0008499535,0.00001890455,0.00008263007,0.00003116053,0.002743149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2759918,"threshold_uncertainty_score":0.6324368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02501780989997436,"score_gpt":0.2742221812195865,"score_spread":0.2492043713196121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}