{"id":"W2059963928","doi":"10.3389/fimmu.2015.00061","title":"The Environment of Regulatory T Cell Biology: Cytokines, Metabolites, and the Microbiome","year":2015,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Immune system; Microbiome; Biology; Function (biology); Retinoic acid; Cell biology; Immunology; Immune tolerance; Regulatory T cell; Innate immune system; Acquired immune system; T cell; Bioinformatics; Cell culture; IL-2 receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003499156,0.0006924809,0.0008817142,0.001131593,0.0002922528,0.001004242,0.0005098145,0.001078531,0.002230141],"category_scores_gemma":[0.0004198476,0.0001914096,0.0002538041,0.001193657,0.0005349824,0.001162436,0.0006607422,0.00141787,0.001473854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005425478,"about_ca_system_score_gemma":0.0009448688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000551288,"about_ca_topic_score_gemma":0.0009017804,"domain_scores_codex":[0.9998645,0.00002860695,0.00001554968,0.00002139501,0.00005214348,0.00001793925],"domain_scores_gemma":[0.9998247,0.00006533496,0.00002492636,0.000005516015,0.00005057334,0.00002900983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007689613,0.00005372726,0.0003068675,0.01027261,0.00005488798,0.0002341634,0.0001045746,0.0002512843,0.006355663,0.005817519,0.03359792,0.9428738],"study_design_scores_gemma":[0.000008253487,0.00006337085,0.001004518,0.002083791,0.00003904746,0.001124833,0.00009323897,0.00006950144,0.0008820952,0.003058167,0.9915589,0.00001422144],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001334103,0.9981827,0.0001580673,0.0003753939,0.0003533906,0.000001989935,0.000008561548,0.000007145778,0.0007793279],"genre_scores_gemma":[0.001259922,0.9970969,0.0002005611,0.0002427766,0.0003474373,0.00000498799,0.00001778898,0.000001355859,0.0008283248],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002230141,"threshold_uncertainty_score":0.007460535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01143088927615123,"score_gpt":0.2293274715159296,"score_spread":0.2178965822397784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}