{"id":"W2060039717","doi":"10.1021/bi100296z","title":"Core Histone Hyperacetylation Impacts Cooperative Behavior and High-Affinity Binding of Histone H1 to Chromatin","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thunder Bay Regional Health Sciences Centre; Athabasca University; NOSM University; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Acetylation; Histone; Histone H1; Chromatin; Fluorescence recovery after photobleaching; Histone deacetylase; Biophysics; Chemistry; Histone H4; Cell biology; Biology; Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001386993,0.0002117812,0.0001645855,0.00008439789,0.0001176583,0.0002983655,0.0002218215,0.0001875616,0.0008951413],"category_scores_gemma":[0.0003283297,0.0001539588,0.0001988037,0.00008411235,0.000173948,0.0002412928,0.0001313359,0.0002901487,0.0001602106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004014029,"about_ca_system_score_gemma":0.0001721326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002454747,"about_ca_topic_score_gemma":0.002368182,"domain_scores_codex":[0.9998882,0.00001434969,0.000005210904,0.0000293009,0.00003611001,0.00002675138],"domain_scores_gemma":[0.9998893,0.00003383964,0.00003247744,0.00001539625,0.00001370899,0.00001531544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007058026,0.00001344567,0.0007752272,0.00001359726,0.00000828516,0.00001342701,0.00001152112,0.0008968734,0.9972568,0.00007861266,0.000007198107,0.0008544529],"study_design_scores_gemma":[0.000005041555,0.0001309172,0.01328902,0.000001632772,0.00001504233,0.00004785055,0.00002464794,0.01829149,0.9678735,0.0000580716,0.0002551086,0.000007720074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982023,0.0001308605,0.001413752,0.00001019448,0.000001988218,0.000002417964,0.00003112814,0.00001662084,0.0001907548],"genre_scores_gemma":[0.9993492,0.00007719013,0.000364033,0.00000284284,6.142928e-7,0.000001395148,0.00003618853,0.000004915975,0.0001636317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002454747,"threshold_uncertainty_score":0.004880965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01212485468293251,"score_gpt":0.2906748735867979,"score_spread":0.2785500189038654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}