{"id":"W2060039717","doi":"10.1021/bi100296z","title":"Core Histone Hyperacetylation Impacts Cooperative Behavior and High-Affinity Binding of Histone H1 to Chromatin","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thunder Bay Regional Health Sciences Centre; Athabasca University; NOSM University; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Acetylation; Histone; Histone H1; Chromatin; Fluorescence recovery after photobleaching; Histone deacetylase; Biophysics; Chemistry; Histone H4; Cell biology; Biology; Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001275504,0.000194566,0.0002014944,0.00003471411,0.00009626118,0.00002002935,0.0001592242,0.0002530602,0.00004394216],"category_scores_gemma":[0.0001564889,0.0002040357,0.00004916637,0.00008552614,0.0001266876,0.000004088066,0.0001422483,0.0001441382,0.000005446543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003978281,"about_ca_system_score_gemma":0.0001174473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005157353,"about_ca_topic_score_gemma":0.00005093569,"domain_scores_codex":[0.9990548,0.00001065558,0.0002705809,0.000348416,0.0001144867,0.0002010674],"domain_scores_gemma":[0.9991501,0.000011865,0.0001551538,0.0003823894,0.0001356296,0.000164836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003165489,0.00008967002,0.002230649,0.00004732657,0.00001824473,0.00000180223,0.00007178722,0.00001093472,0.9964042,0.00004070814,0.000445848,0.0006071904],"study_design_scores_gemma":[0.0004532687,0.0001482115,0.01152679,0.00001771648,0.00003005656,0.00003413556,0.00007154464,0.00007485879,0.9871085,0.00000675622,0.0002877021,0.0002404365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989687,0.0001482821,0.00007889455,0.0000540617,0.0001435522,0.0001984079,0.0001675019,0.00001274474,0.0002278904],"genre_scores_gemma":[0.9950932,0.0000315405,0.003706054,0.00004719448,0.0001351747,0.00002545015,0.0004229625,0.00002715657,0.0005112206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009296141,"threshold_uncertainty_score":0.8320335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01212485468293251,"score_gpt":0.2906748735867979,"score_spread":0.2785500189038654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}