{"id":"W2060063893","doi":"10.1210/en.2008-1088","title":"Up-Regulation of Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Human Endometriotic Cells by Macrophage Migration Inhibitory Factor: Involvement of Novel Kinase Signaling Pathways","year":2009,"lang":"en","type":"article","venue":"Endocrinology","topic":"Endometriosis Research and Treatment","field":"Medicine","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; Hôpital Saint-François d'Assise; Centre hospitalier universitaire de Québec","funders":"","keywords":"Proinflammatory cytokine; MAPK/ERK pathway; Macrophage migration inhibitory factor; Prostaglandin; Endocrinology; Internal medicine; Prostaglandin E; Cyclooxygenase; p38 mitogen-activated protein kinases; Ectopic expression; Biology; Prostaglandin E2; Signal transduction; Chemistry; Cell biology; Inflammation; Cytokine; Medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001589014,0.0002849216,0.0002598456,0.000206698,0.0001280902,0.0002379981,0.00008143503,0.0002359679,0.0008151908],"category_scores_gemma":[0.0001106783,0.0001183521,0.0002379173,0.0001845784,0.0001732244,0.000177302,0.0001800053,0.0002924309,0.0002273655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001594488,"about_ca_system_score_gemma":0.000147526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002931156,"about_ca_topic_score_gemma":0.000333533,"domain_scores_codex":[0.9998937,0.00002088181,0.0000104048,0.00001330708,0.00002137661,0.00004040216],"domain_scores_gemma":[0.9999572,0.000008313333,0.000008667827,0.000006184429,0.000008323511,0.00001126939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005029637,0.00004579001,0.0005436374,0.00009861718,0.000005125317,0.0001855191,0.00003499187,0.00002507268,0.9957595,0.00007197202,0.00003137458,0.002695424],"study_design_scores_gemma":[0.0001138583,0.000974384,0.03122137,0.00001802652,0.00003999241,0.001306412,0.0001250863,0.0009488754,0.9596245,0.0001048309,0.005511781,0.00001092776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844468,0.01154258,0.002475334,0.0001472852,0.00005307208,0.00005775024,0.0002071641,0.00002846406,0.00104152],"genre_scores_gemma":[0.9919105,0.004278666,0.002190905,0.00007106286,0.00003209824,0.00008826458,0.000244931,0.000002731162,0.001180854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008151908,"threshold_uncertainty_score":0.002727032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03041203779059404,"score_gpt":0.2875009042732818,"score_spread":0.2570888664826878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}