{"id":"W2060082838","doi":"10.1007/s00280-004-0776-3","title":"Inhibition of ?-glutamyl transpeptidase activity decreases intracellular cysteine levels in cervical carcinoma","year":2004,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Cysteine; In vivo; Glutathione; Intracellular; Cell culture; In vitro; Enzyme inhibitor; Enzyme; Biology; Biochemistry; Internal medicine; Chemistry; Molecular biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001155326,0.0001721704,0.0002539196,0.00006334031,0.00003259709,0.000003487661,0.00009619555,0.0002286414,0.0001741246],"category_scores_gemma":[0.000006476519,0.0001724232,0.00005963377,0.000107478,0.000264569,0.000006244892,0.00002957775,0.0001357868,7.706207e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004601115,"about_ca_system_score_gemma":0.0001252061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000165405,"about_ca_topic_score_gemma":0.0001266822,"domain_scores_codex":[0.9990457,0.00009863466,0.000209745,0.0003483178,0.00005465872,0.0002429911],"domain_scores_gemma":[0.999642,0.00002465872,0.00008293728,0.0001267376,0.00004348503,0.00008019614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008630503,0.0002019503,0.00580068,0.000061556,0.00005496775,0.00001569467,0.0001834272,0.0001444583,0.9864622,0.00002590011,0.00003108848,0.006155012],"study_design_scores_gemma":[0.004973619,0.0004647276,0.0135347,0.00001789421,0.00002110075,0.00002912648,0.00002056985,0.00003161604,0.9790304,0.0002974105,0.001407161,0.0001717328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948816,0.002892649,0.0007418129,0.0009323206,0.0001823651,0.0002311737,0.00004478176,0.000009070955,0.00008416858],"genre_scores_gemma":[0.9970497,0.001405193,0.0002093379,0.0009544356,0.0002614034,0.00005708095,0.0000255395,0.00001932877,0.00001793689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007734016,"threshold_uncertainty_score":0.7031212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01858617316590961,"score_gpt":0.2935874404988378,"score_spread":0.2750012673329282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}