{"id":"W2060084495","doi":"10.1002/chin.201222145","title":"ChemInform Abstract: Polycyclic Quinolones. Part 1. Thieno[2,3‐b]benzo[h]quinoline Derivatives: Design, Synthesis, Preliminary in vitro and in silico Studies.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Quinoline; In silico; Chemistry; Combinatorial chemistry; In vitro; Stereochemistry; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000153605,0.0008983446,0.0003670202,0.0008187363,0.0003011982,0.0004390891,0.0005224302,0.0004456106,0.04885674],"category_scores_gemma":[0.0001595491,0.0003234192,0.0002322763,0.000659635,0.0002195247,0.0003164435,0.0003116852,0.0005654066,0.01230792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005340134,"about_ca_system_score_gemma":0.0006526828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001508256,"about_ca_topic_score_gemma":0.002904276,"domain_scores_codex":[0.9999251,0.00001164097,0.000003667259,0.00001428032,0.00003458417,0.00001067195],"domain_scores_gemma":[0.999943,0.000009379964,0.00001596753,0.00000510894,0.00001237574,0.00001417163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002157293,0.0005467154,0.001156652,0.004081861,0.0001156305,0.0006214856,0.0000894405,0.006125539,0.490132,0.008317439,0.05311219,0.4335437],"study_design_scores_gemma":[0.001887699,0.002782014,0.006963767,0.0002981168,0.0003089084,0.001531544,0.00004108728,0.004036242,0.4119685,0.001814695,0.5682951,0.00007239603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.192813,0.1574049,0.08900732,0.005723307,0.001543756,0.002976661,0.05774626,0.01031354,0.4824712],"genre_scores_gemma":[0.5659668,0.1258008,0.05913218,0.002403773,0.001128042,0.0009812411,0.05239201,0.0005020882,0.191693],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.04885674,"threshold_uncertainty_score":0.1634421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05637035413955658,"score_gpt":0.2762879528461546,"score_spread":0.219917598706598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}