{"id":"W2060156579","doi":"10.1016/j.abb.2012.06.010","title":"Influence of main channel structure on H2O2 access to the heme cavity of catalase KatE of Escherichia coli","year":2012,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"National Research Council Canada; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Catalase; Escherichia coli; Heme; Chemistry; Channel (broadcasting); Hemeprotein; Microbiology; Biochemistry; Enzyme; Biology; Computer science; Telecommunications; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000501688,0.0001197873,0.000167815,0.00001737552,0.00002767937,0.000002363344,0.0002076439,0.00007094656,0.000001178701],"category_scores_gemma":[0.00001886534,0.00009085959,0.00006956325,0.00009618439,0.0002494727,0.000007022863,0.00008179081,0.00005385451,7.402622e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001543634,"about_ca_system_score_gemma":0.00003078096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002865498,"about_ca_topic_score_gemma":0.000003097643,"domain_scores_codex":[0.9993919,0.00001600542,0.0002118427,0.0001435254,0.0001055097,0.0001312096],"domain_scores_gemma":[0.999405,0.00001648058,0.0001997913,0.0002656704,0.00005466224,0.00005840725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002437886,0.00009770905,0.002036035,0.0002827246,0.00003815991,1.03629e-7,0.0002823049,0.000629239,0.9958963,0.00005382506,0.00001784794,0.0004219969],"study_design_scores_gemma":[0.0001796324,0.0001237991,0.04575624,0.00005681207,0.00002207774,7.642331e-7,0.00007456955,0.0000226856,0.9534837,0.000154127,0.00003863896,0.00008692448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990938,0.0001267965,0.0001012146,0.00006320862,0.0000237387,0.0001120982,0.0004162654,0.000001522259,0.0000613123],"genre_scores_gemma":[0.9995182,0.00005480764,0.00009998837,0.00004310228,0.00008608667,0.000003221517,0.000157779,0.000007104969,0.00002976479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0437202,"threshold_uncertainty_score":0.3705147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006866257418953995,"score_gpt":0.229094155899409,"score_spread":0.222227898480455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}