{"id":"W2060164191","doi":"10.1016/s0168-9525(00)02106-5","title":"Internal ribosome initiation of translation and the control of cell death","year":2000,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":237,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Children's Hospital of Eastern Ontario","funders":"Medical Research Council","keywords":"Internal ribosome entry site; Biology; Translation (biology); Cell biology; Ribosome; Messenger RNA; Protein biosynthesis; Initiation factor; Untranslated region; Programmed cell death; Eukaryotic translation; Eukaryotic initiation factor; EIF4E; Ribosomal binding site; Apoptosis; Genetics; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002047145,0.0001011476,0.0006897438,0.0003385475,0.00001276133,0.000003079566,0.00005859195,0.0001540612,0.00008838227],"category_scores_gemma":[0.000009384669,0.00006286133,0.0001398439,0.0002209426,0.0001627499,0.0000114659,0.000009645778,0.0002653935,0.000001586908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001663304,"about_ca_system_score_gemma":0.00005121995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002636688,"about_ca_topic_score_gemma":0.000006317742,"domain_scores_codex":[0.9991121,0.000170807,0.0004416621,0.00009562595,0.00009302807,0.00008673725],"domain_scores_gemma":[0.9995237,0.0001272697,0.000142402,0.0001584053,0.00003355374,0.0000146669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008962079,0.00005882118,0.0002950724,0.001091682,0.00006901484,9.413675e-7,0.00008179597,0.000002686259,0.000008792794,0.00003674932,0.000004429949,0.9982604],"study_design_scores_gemma":[0.02971835,0.003554325,0.01120827,0.01379961,0.006069808,0.0002193626,0.00005793395,0.003769588,0.0004294217,0.0004546416,0.9301676,0.0005510586],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001333354,0.9935268,0.00008833498,0.00002413648,0.00003134558,0.0002316213,0.00002797868,0.000002594243,0.004733888],"genre_scores_gemma":[0.05930604,0.9402856,0.00009480552,0.000005359869,0.00002594343,0.00001739107,0.00003873869,0.00001004585,0.000216039],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9977093,"threshold_uncertainty_score":0.256341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09433848648971964,"score_gpt":0.391450862935361,"score_spread":0.2971123764456414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}