{"id":"W2060169839","doi":"10.1021/ic702057q","title":"Synthesis, Characterization and Stat3 Inhibitory Properties of the Prototypical Platinum(IV) Anticancer Drug, [PtCl<sub>3</sub>(NO<sub>2</sub>)(NH<sub>3</sub>)<sub>2</sub>] (CPA-7)","year":2008,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Platinum; Stereochemistry; Nuclear magnetic resonance spectroscopy; Crystallography; Crystal structure; Anticancer drug; Characterization (materials science); Single crystal; Recrystallization (geology); Drug; Nanotechnology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004991821,0.001233027,0.001420911,0.00007464811,0.0007193827,0.0001494203,0.0009518916,0.001230284,0.0001515307],"category_scores_gemma":[0.001451489,0.0009451279,0.0004959228,0.000566533,0.0014484,0.0004630347,0.0007541442,0.00144728,0.00008973884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005105725,"about_ca_system_score_gemma":0.0006497541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001842408,"about_ca_topic_score_gemma":0.00001793077,"domain_scores_codex":[0.9940476,0.0002358078,0.001515308,0.001753399,0.001183261,0.001264572],"domain_scores_gemma":[0.9960408,0.0005171338,0.001115009,0.001389969,0.0004653129,0.0004717251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005449957,0.0008547252,0.009965682,0.001510537,0.0002268198,0.00003518235,0.0003241369,0.000001817081,0.9727734,0.000002892547,0.0004335437,0.01332621],"study_design_scores_gemma":[0.0009278527,0.00005493329,0.01539221,0.001088016,0.0001919826,0.0001799179,0.0001998123,0.000124694,0.9801574,0.00003499579,0.0004278263,0.00122033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966859,0.0004935955,0.00001624527,0.0004478558,0.0002291539,0.0009591092,0.0004140414,0.0003559334,0.0003982045],"genre_scores_gemma":[0.9960908,0.001652133,0.00001861489,0.0001875358,0.001241897,0.0004449543,0.0001201026,0.000190273,0.00005371774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01210588,"threshold_uncertainty_score":0.9992999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122988139631581,"score_gpt":0.183706343297778,"score_spread":0.1714075293346199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}