{"id":"W2060169839","doi":"10.1021/ic702057q","title":"Synthesis, Characterization and Stat3 Inhibitory Properties of the Prototypical Platinum(IV) Anticancer Drug, [PtCl<sub>3</sub>(NO<sub>2</sub>)(NH<sub>3</sub>)<sub>2</sub>] (CPA-7)","year":2008,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Platinum; Stereochemistry; Nuclear magnetic resonance spectroscopy; Crystallography; Crystal structure; Anticancer drug; Characterization (materials science); Single crystal; Recrystallization (geology); Drug; Nanotechnology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001078803,0.0001344155,0.0001515851,0.0001275839,0.0001297904,0.0001657078,0.00014498,0.0001626726,0.000563573],"category_scores_gemma":[0.0001677583,0.00006647666,0.0001167736,0.0001462686,0.0002000613,0.0001463761,0.00008583155,0.0001929889,0.0001795317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002460601,"about_ca_system_score_gemma":0.0002326099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003799296,"about_ca_topic_score_gemma":0.0006723845,"domain_scores_codex":[0.9999269,0.000009621187,0.000005937477,0.00001561464,0.00003446958,0.000007376525],"domain_scores_gemma":[0.9999031,0.0000186302,0.00002783414,0.00001441192,0.00001809655,0.00001782789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006171768,0.0000197337,0.0001254308,0.00002884152,0.000003135479,0.00001621499,0.00001042678,0.0001301241,0.9963455,0.00006137714,0.00002300076,0.003174591],"study_design_scores_gemma":[0.000005898565,0.0002591435,0.0008802124,0.000001170942,0.000007468862,0.0001381465,0.00000499577,0.0002624231,0.9972056,0.00001506922,0.001217356,0.000002414764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897118,0.00214323,0.00542137,0.00007170154,0.00001704686,0.00007615822,0.0005423477,0.00004527627,0.001971186],"genre_scores_gemma":[0.988393,0.001226786,0.007974961,0.00003664706,0.000009443348,0.00003111848,0.0007109638,0.00002422265,0.001592861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000563573,"threshold_uncertainty_score":0.001885295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122988139631581,"score_gpt":0.183706343297778,"score_spread":0.1714075293346199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}