{"id":"W2060234245","doi":"10.1021/bi700317k","title":"Tilted, Extended, and Lying in Wait:  The Membrane-Bound Topology of Residues Lys-381−Ser-405 of the Colicin E1 Channel Domain","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"University of Guelph","keywords":"Colicin; Chemistry; Helix (gastropod); Crystallography; Lipid bilayer; Membrane; Membrane protein; Protein structure; Biophysics; Biology; Biochemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007277309,0.0001028488,0.000136748,0.0001063322,0.0001032519,0.0002507754,0.000145668,0.0001433177,0.0005781273],"category_scores_gemma":[0.0002688589,0.000112992,0.00009941157,0.0001256334,0.0002930533,0.0002934128,0.0001565341,0.0003810347,0.00009862729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002008415,"about_ca_system_score_gemma":0.0001099132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004819647,"about_ca_topic_score_gemma":0.0004405162,"domain_scores_codex":[0.9999522,0.000005568063,0.00000226442,0.00001281121,0.00001510606,0.00001206908],"domain_scores_gemma":[0.9998443,0.00003235924,0.00005393713,0.00001170026,0.00001727025,0.00004037185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003234905,0.00002090621,0.002956315,0.00002377291,0.00001042775,0.0001442255,0.00004872959,0.0006214902,0.9942157,0.0001364586,0.00001762013,0.001480985],"study_design_scores_gemma":[0.000038739,0.0005883152,0.1158906,0.00001148608,0.0000401155,0.0007267793,0.0003390203,0.02165062,0.8593919,0.0005354852,0.0007467647,0.00004011259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995242,0.0000234549,0.000352379,0.000003472798,9.874732e-7,6.8475e-7,0.00001505933,0.000004754943,0.00007490288],"genre_scores_gemma":[0.9995875,0.00002219428,0.0002426822,0.000005981706,7.493013e-7,0.000001045449,0.00005083064,0.000003648918,0.00008539053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005781273,"threshold_uncertainty_score":0.001934052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00806305594962783,"score_gpt":0.2551212626330715,"score_spread":0.2470582066834437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}