{"id":"W2060361484","doi":"10.1021/bi800439t","title":"Interactions between the Three CIN85 SH3 Domains and Ubiquitin: Implications for CIN85 Ubiquitination","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Canada Research Chairs; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Ubiquitin; SH3 domain; Cell biology; Endocytosis; Ubiquitin ligase; Signal transducing adaptor protein; Chemistry; Plasma protein binding; Biology; Phosphorylation; Biochemistry; Receptor; Proto-oncogene tyrosine-protein kinase Src","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002191744,0.0003700974,0.0002965058,0.000228861,0.0006979609,0.0009758719,0.0006021222,0.0006706499,0.002206712],"category_scores_gemma":[0.0002835993,0.0002213906,0.0003724186,0.0001816402,0.0005774161,0.000780218,0.0004763772,0.0004767365,0.0002949611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001715718,"about_ca_system_score_gemma":0.0004474291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002703059,"about_ca_topic_score_gemma":0.003183749,"domain_scores_codex":[0.9998353,0.0000194674,0.000008050553,0.00002666109,0.00004442088,0.00006597486],"domain_scores_gemma":[0.9998838,0.00003250512,0.00002395687,0.00001055388,0.00001329992,0.00003587596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000677324,0.00006660093,0.004247962,0.0001045148,0.00002881059,0.001000425,0.00009016976,0.002613251,0.9766261,0.009171765,0.0001721666,0.005200861],"study_design_scores_gemma":[0.00005453084,0.0001072217,0.02160854,0.00002232918,0.00005202372,0.001526421,0.0002432242,0.02116775,0.9476172,0.004150517,0.003407523,0.000042602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909114,0.001756142,0.003160249,0.0006395276,0.00002066681,0.000007192671,0.00005633602,0.00003297798,0.00341546],"genre_scores_gemma":[0.9984866,0.0002136026,0.0004665456,0.00006197053,0.000002727861,0.000002479543,0.00003010681,0.000002414843,0.0007334933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002703059,"threshold_uncertainty_score":0.01244849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02343194627373742,"score_gpt":0.2660122055517856,"score_spread":0.2425802592780481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}