{"id":"W2060367291","doi":"10.1006/bbrc.2001.5262","title":"Identification of DNA–Protein Interactions in the 5′ Flanking and 5′ Untranslated Regions of the Human Multidrug Resistance Protein (MRP1) Gene: Evaluation of a Putative Antioxidant Response Element/AP-1 Binding Site","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Molecular biology; Biology; 5' flanking region; Response element; Footprinting; Gene; DNA footprinting; Electrophoretic mobility shift assay; Binding site; Untranslated region; Promoter; Transcription (linguistics); Transcription factor; Enhancer; Nuclear protein; Reporter gene; Regulatory sequence; Gene expression; Genetics; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000340775,0.0003478681,0.0004529644,0.0004301268,0.0005051136,0.0003507351,0.0003937013,0.0006860861,0.002390105],"category_scores_gemma":[0.0006693581,0.0004197681,0.0006345239,0.0003144584,0.0004285204,0.0002942294,0.0002860681,0.001023501,0.001278384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003533567,"about_ca_system_score_gemma":0.0002833353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000769789,"about_ca_topic_score_gemma":0.001455297,"domain_scores_codex":[0.9996697,0.00007477838,0.00001706526,0.0000991697,0.00008292089,0.0000564579],"domain_scores_gemma":[0.9992945,0.0003306456,0.0001313796,0.00004904906,0.00007335095,0.0001209557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00017665,0.00004957293,0.0004239377,0.00004529773,0.000008609449,0.00008714594,0.00003561371,0.00007930749,0.9976842,0.0001491814,0.00002441507,0.001236079],"study_design_scores_gemma":[0.00006107697,0.0004088294,0.03010039,0.00002873468,0.000073289,0.0008875339,0.00008937113,0.002647508,0.96211,0.0003683029,0.003200819,0.00002410397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984224,0.001875203,0.01198201,0.0001849003,0.00002708314,0.00004930549,0.0003738622,0.00005759495,0.001225988],"genre_scores_gemma":[0.9847994,0.0002984393,0.01192484,0.0001886003,0.00002119112,0.00004384484,0.001103968,0.00002489169,0.001594752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002390105,"threshold_uncertainty_score":0.007995725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09234549875958772,"score_gpt":0.402436414777199,"score_spread":0.3100909160176113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}