{"id":"W2060409719","doi":"10.1007/s10495-011-0669-y","title":"Hepatocellular apoptosis in mice is associated with early upregulation of mitochondrial glucose metabolism","year":2011,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital Saint-Luc","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Ministère de l'Éducation, du Loisir et du Sport Québec","keywords":"Apoptosis; Downregulation and upregulation; Programmed cell death; Biology; Ex vivo; Hepatocyte; Mitochondrion; Pyruvate dehydrogenase complex; Internal medicine; Cytochrome c; Citric acid cycle; Endocrinology; Cell biology; Chemistry; Metabolism; Biochemistry; Medicine; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001260253,0.0001828225,0.0002433414,0.00009923754,0.00004352611,0.000009946191,0.0001450703,0.0002558691,0.00006139973],"category_scores_gemma":[0.00002995802,0.000163564,0.000109677,0.0002407994,0.0000548444,0.00001255399,0.00005176436,0.00006887524,0.000004127813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001599826,"about_ca_system_score_gemma":0.00003502511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004444692,"about_ca_topic_score_gemma":0.00003925482,"domain_scores_codex":[0.9988443,0.0000706962,0.0003068859,0.0003496832,0.0001983757,0.0002301229],"domain_scores_gemma":[0.9993203,0.000009112918,0.0002007762,0.0002802002,0.0001291521,0.00006045456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002245708,0.0001597909,0.005910391,0.000009576579,0.0001027817,3.693793e-7,0.0004926182,0.00001277823,0.9918606,0.0002119809,0.00006284888,0.0009516443],"study_design_scores_gemma":[0.001109836,0.0002290517,0.02473968,0.00003349622,0.0000849409,8.10037e-7,0.00004696111,0.0001527682,0.9728445,0.0002346143,0.0003156798,0.0002076983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970903,0.0002434967,0.001793311,0.00002057843,0.0001615213,0.0002928566,0.00001758892,0.00001261379,0.0003677472],"genre_scores_gemma":[0.9964513,0.0001025232,0.002865193,0.00004517584,0.00007835827,0.00003238688,0.0001227454,0.00003084417,0.0002714291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01901618,"threshold_uncertainty_score":0.6669946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01290166957308651,"score_gpt":0.2017513665578624,"score_spread":0.1888496969847759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}