{"id":"W2060417514","doi":"10.1002/cbic.201500091","title":"Direct Staudinger–Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De‐N‐acetylases","year":2015,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Peptidoglycan; Enzyme; Biofilm; Biochemistry; Escherichia coli; Bacteria; Microbiology; Lysin; Chemistry; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003884551,0.000344541,0.00045617,0.00005216975,0.00006792902,0.00005007058,0.0002982007,0.0003184714,0.0003534208],"category_scores_gemma":[0.001127105,0.00035276,0.0002233506,0.0003052364,0.0001863569,0.0001720655,0.0001228734,0.0002255798,0.00004270093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003359816,"about_ca_system_score_gemma":0.0002993681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004438715,"about_ca_topic_score_gemma":0.000004878217,"domain_scores_codex":[0.9981856,0.00001943424,0.0004645882,0.0004996239,0.000396907,0.0004338404],"domain_scores_gemma":[0.9982956,0.0002416314,0.0003183255,0.0005819696,0.0002406917,0.0003217726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001813247,0.0001796198,0.0007226123,0.0003084109,0.0001013266,0.00001400639,0.000642727,0.000009945526,0.9935042,0.00001798975,0.002456602,0.001861225],"study_design_scores_gemma":[0.0004987311,0.00002785042,0.00001394628,0.0001839253,0.00009044102,0.000023538,0.001711868,0.00005124162,0.9880738,0.0002273297,0.008717981,0.0003793074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9282867,0.001527807,0.00000287378,0.0001101288,0.0001132932,0.00006677791,0.00004198467,0.0001978698,0.06965251],"genre_scores_gemma":[0.9945545,0.000140181,0.0002511326,0.00003350547,0.0002293984,0.00005213985,0.00008718934,0.00005779594,0.004594209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0662677,"threshold_uncertainty_score":0.9998924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01916321979599931,"score_gpt":0.2440324982436367,"score_spread":0.2248692784476374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}