{"id":"W2060417514","doi":"10.1002/cbic.201500091","title":"Direct Staudinger–Phosphonite Reaction Provides Methylphosphonamidates as Inhibitors of CE4 De‐N‐acetylases","year":2015,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Peptidoglycan; Enzyme; Biofilm; Biochemistry; Escherichia coli; Bacteria; Microbiology; Lysin; Chemistry; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002620601,0.0004030014,0.0002467177,0.0001609514,0.00009995329,0.0002152125,0.0004402788,0.0003465542,0.001097168],"category_scores_gemma":[0.0002367815,0.0001937308,0.0002077555,0.0001431671,0.000189689,0.0003214274,0.0002474812,0.0005148337,0.0004032211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003265892,"about_ca_system_score_gemma":0.0002610753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007682589,"about_ca_topic_score_gemma":0.001436762,"domain_scores_codex":[0.9998657,0.00003349005,0.00001029524,0.00001917741,0.00003527485,0.00003616255],"domain_scores_gemma":[0.9999398,0.00001939259,0.00001281527,0.000007245058,0.00001051712,0.00001018079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004281894,0.0001145419,0.0001106808,0.0001923261,0.0000259951,0.0001245563,0.00004793681,0.001208978,0.9839722,0.00157658,0.0002993683,0.01189865],"study_design_scores_gemma":[0.0000566151,0.0006377167,0.000252432,0.000006952598,0.00001039338,0.000111539,0.000007218796,0.00138191,0.9925314,0.00008880073,0.00490764,0.000007403727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.950904,0.008511666,0.02419074,0.0003146588,0.000154511,0.0001908087,0.0003473425,0.0002835795,0.01510272],"genre_scores_gemma":[0.9841531,0.003792766,0.006641534,0.00006456658,0.00001463427,0.00005336722,0.0002413776,0.00002189067,0.005016756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001097168,"threshold_uncertainty_score":0.003670394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01916321979599931,"score_gpt":0.2440324982436367,"score_spread":0.2248692784476374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}