{"id":"W2060444223","doi":"10.1016/j.molcel.2015.03.023","title":"Transcriptional Elongation Factor ENL Phosphorylated by ATM Recruits Polycomb and Switches Off Transcription for DSB Repair","year":2015,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Aging","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Biology; Ubiquitin ligase; Cell biology; Transcription factor; Ubiquitin; BMI1; Phosphorylation; Psychological repression; Transcription (linguistics); Repressor; Elongation factor; Molecular biology; Genetics; Gene; Gene expression; RNA; Ribosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002163154,0.0003783058,0.0002522293,0.0002801698,0.0004046284,0.0008757167,0.0004467348,0.000308356,0.007748652],"category_scores_gemma":[0.0002334462,0.0003346941,0.0003438747,0.0001450115,0.0003499091,0.0007344112,0.0007436132,0.000926937,0.002732987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005995581,"about_ca_system_score_gemma":0.0001866494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003817899,"about_ca_topic_score_gemma":0.0008827779,"domain_scores_codex":[0.9998176,0.00001147767,0.000009207284,0.00006201415,0.00003237739,0.00006744379],"domain_scores_gemma":[0.9998416,0.00001852412,0.00003143381,0.00002578337,0.0000201834,0.0000624296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002964748,0.00001937145,0.0008085584,0.00002523277,0.000006146664,0.0001685749,0.0000235898,0.0000729111,0.9942121,0.0008248125,0.0002851964,0.003257064],"study_design_scores_gemma":[0.00002583809,0.00007938179,0.01056338,0.000005364414,0.000007777913,0.0002308271,0.00007188041,0.0008272762,0.9821677,0.000380609,0.005632135,0.00000793424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750882,0.002288802,0.01011512,0.0004599794,0.000190094,0.00003081687,0.0007134798,0.0006382345,0.01047528],"genre_scores_gemma":[0.986032,0.0003829453,0.001685126,0.00008450047,0.00003014543,0.00001100954,0.0009333033,0.00009767083,0.01074347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007748652,"threshold_uncertainty_score":0.02592188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068483736452423,"score_gpt":0.2451147712078541,"score_spread":0.2244299338433298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}