{"id":"W2060444223","doi":"10.1016/j.molcel.2015.03.023","title":"Transcriptional Elongation Factor ENL Phosphorylated by ATM Recruits Polycomb and Switches Off Transcription for DSB Repair","year":2015,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Aging","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Biology; Ubiquitin ligase; Cell biology; Transcription factor; Ubiquitin; BMI1; Phosphorylation; Psychological repression; Transcription (linguistics); Repressor; Elongation factor; Molecular biology; Genetics; Gene; Gene expression; RNA; Ribosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002344471,0.0002026689,0.0001547442,0.00004121815,0.00006447723,0.00003401315,0.00008608261,0.0002509413,0.000008584319],"category_scores_gemma":[0.000046283,0.0002146251,0.0001362969,0.00007461648,0.00004441704,0.000009568088,0.00001524901,0.00007618153,0.000003402475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002630649,"about_ca_system_score_gemma":0.0000692315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002388045,"about_ca_topic_score_gemma":0.00001242295,"domain_scores_codex":[0.9988098,0.00006619746,0.0002587086,0.0004341799,0.0001989833,0.000232102],"domain_scores_gemma":[0.9993543,0.000009254614,0.0000826871,0.0002175353,0.0001688181,0.0001673922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000149658,0.00009298979,0.0006292036,0.00002942099,0.00003999255,9.038545e-7,0.000204039,0.00004802659,0.9952869,0.00003430092,0.0005578553,0.002926649],"study_design_scores_gemma":[0.001298607,0.0005023026,0.0007034061,0.000007923657,0.00004629649,0.000001113625,0.00004921681,0.0005358674,0.9186278,0.0003095614,0.07766946,0.0002484623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9368756,0.0184425,0.0433833,0.0001504105,0.0001584019,0.0004997879,0.0001028288,0.0000308674,0.0003562399],"genre_scores_gemma":[0.9946586,0.0005538133,0.002497015,0.0001480705,0.00006627242,0.00006103843,0.001023808,0.00004243818,0.0009488832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0771116,"threshold_uncertainty_score":0.8752158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02068483736452423,"score_gpt":0.2451147712078541,"score_spread":0.2244299338433298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}