{"id":"W2060473917","doi":"10.1016/j.jaci.2011.04.029","title":"Lung dendritic cells induce TH17 cells that produce TH2 cytokines, express GATA-3, and promote airway inflammation","year":2011,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Immunology; Ovalbumin; Inflammation; Dendritic cell; Lymph; CD40; Medicine; Bronchoalveolar lavage; Adoptive cell transfer; Immune system; Eosinophil; Interleukin 17; Allergic inflammation; Lung; T cell; Biology; Cytotoxic T cell; In vitro; Pathology; Asthma; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005168937,0.0007794474,0.0006786434,0.0006585477,0.0004013812,0.0007616534,0.0001947439,0.0008260517,0.004506309],"category_scores_gemma":[0.0003033532,0.000385658,0.0008175483,0.000236751,0.0003784378,0.0004232056,0.0006853516,0.003480618,0.002093833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005761028,"about_ca_system_score_gemma":0.0004622619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004193474,"about_ca_topic_score_gemma":0.001057065,"domain_scores_codex":[0.9990729,0.0001447845,0.00005651968,0.0001314241,0.0002360845,0.0003581934],"domain_scores_gemma":[0.9995996,0.00005081652,0.00005364592,0.00005464685,0.00007837906,0.0001629204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003183903,0.000162098,0.001404213,0.0001286379,0.00002397474,0.0001828403,0.00004015346,0.0001055255,0.9921896,0.0001936593,0.0006304882,0.004620417],"study_design_scores_gemma":[0.0004313979,0.001033657,0.01621017,0.00007406204,0.0001173946,0.0008906093,0.0002789437,0.001569092,0.9649716,0.0005716457,0.0138287,0.00002275362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9661125,0.006605388,0.008931913,0.001366295,0.001014977,0.0004906793,0.001833155,0.0004895538,0.01315559],"genre_scores_gemma":[0.9868253,0.001780091,0.00339283,0.0007144945,0.000233781,0.0001274355,0.0007392688,0.00009593102,0.006090979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004506309,"threshold_uncertainty_score":0.01507515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0292029257536078,"score_gpt":0.2746893257608912,"score_spread":0.2454864000072834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}