{"id":"W2060520744","doi":"10.4161/cc.25265","title":"CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Institutes of Health","keywords":"Biology; Cell cycle; Cell biology; E2F; Cyclin-dependent kinase; Retinoblastoma protein; Cyclin-dependent kinase 6; Cyclin E; Cyclin A; Cyclin; Cyclin B1; Cyclin-dependent kinase 1; Cyclin-dependent kinase 2; Kinase; Cell; Protein kinase A; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000110583,0.0002421392,0.0002813924,0.0001642092,0.0001070845,0.00005175091,0.0001261556,0.0001051853,0.0001747177],"category_scores_gemma":[0.0000491858,0.00020834,0.00007660563,0.0003270235,0.00006939312,0.0003045051,0.0001518361,0.0004581896,0.0008491125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001550088,"about_ca_system_score_gemma":0.00008029542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000366704,"about_ca_topic_score_gemma":0.00002655294,"domain_scores_codex":[0.9979969,0.0001187856,0.0002201416,0.0005131004,0.0004743795,0.0006766818],"domain_scores_gemma":[0.9988924,0.00008768225,0.00008435379,0.0004417444,0.00005930632,0.0004345709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000232905,0.001998592,0.01206611,0.0001969528,0.000008718341,0.0004240158,0.0001414208,0.00001584303,0.9658524,9.777093e-7,0.004791555,0.01427052],"study_design_scores_gemma":[0.003318472,0.0009763118,0.05389711,0.0001367747,0.00001402393,0.00003177491,0.00003380844,0.0007988146,0.9394291,0.00003343357,0.001137083,0.0001932974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858612,0.0001501795,0.000005668345,0.0003986317,0.0001055049,0.001047593,0.000005512809,0.0001114947,0.01231424],"genre_scores_gemma":[0.9960753,0.00004573652,0.0001814652,0.00008198512,0.0000701126,0.0001511435,0.00001054952,0.00005837272,0.003325376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.041831,"threshold_uncertainty_score":0.9999288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008463416805034516,"score_gpt":0.2704392374296664,"score_spread":0.2619758206246318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}