{"id":"W2060520744","doi":"10.4161/cc.25265","title":"CASZ1 inhibits cell cycle progression in neuroblastoma by restoring pRb activity","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"National Cancer Institute; National Institutes of Health","keywords":"Biology; Cell cycle; Cell biology; E2F; Cyclin-dependent kinase; Retinoblastoma protein; Cyclin-dependent kinase 6; Cyclin E; Cyclin A; Cyclin; Cyclin B1; Cyclin-dependent kinase 1; Cyclin-dependent kinase 2; Kinase; Cell; Protein kinase A; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001140338,0.0003780379,0.0004386361,0.000279634,0.0001878519,0.0003063979,0.000299037,0.0002489919,0.0008323907],"category_scores_gemma":[0.0001235514,0.0001463831,0.0002311121,0.0001661729,0.000228722,0.0001386891,0.0001527991,0.0007022822,0.0003114844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000638606,"about_ca_system_score_gemma":0.0006029839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003332663,"about_ca_topic_score_gemma":0.007716266,"domain_scores_codex":[0.9998993,0.000009865882,0.00001379306,0.00001741914,0.00003409943,0.00002553179],"domain_scores_gemma":[0.999931,0.00001115325,0.00001766166,0.000007414626,0.000006973751,0.00002576375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001775067,0.00007587066,0.000230563,0.00006089981,0.000008763866,0.00004493409,0.0000159044,0.0001406471,0.9966575,0.00008423897,0.000112289,0.00239085],"study_design_scores_gemma":[0.00004953125,0.000607201,0.005551744,0.000009265828,0.00001548936,0.0001855228,0.00003175237,0.001254239,0.9886786,0.00004443994,0.003567063,0.000005227915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943603,0.002668534,0.0009197989,0.0001263534,0.0000388453,0.00003869951,0.000412803,0.0001627858,0.001271941],"genre_scores_gemma":[0.9915411,0.002517783,0.00190359,0.00004861478,0.00000821946,0.00006590752,0.0008393173,0.00002558186,0.003049989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003332663,"threshold_uncertainty_score":0.006626546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008463416805034516,"score_gpt":0.2704392374296664,"score_spread":0.2619758206246318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}