{"id":"W2060633970","doi":"10.1002/art.10611","title":"Matrix homeostasis in aging normal human ankle cartilage","year":2002,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging","keywords":"Aggrecan; Collagenase; Type II collagen; Cartilage; Proteoglycan; Chemistry; Glycosaminoglycan; Messenger RNA; Extracellular matrix; Molecular biology; Cartilage oligomeric matrix protein; Internal medicine; Endocrinology; Osteoarthritis; Biology; Biochemistry; Anatomy; Pathology; Medicine; Enzyme; Articular cartilage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001775855,0.0002753065,0.0005175283,0.0003060302,0.000198181,0.00006314848,0.0001005145,0.0001320541,0.003452966],"category_scores_gemma":[0.00002840088,0.0002968709,0.0001427801,0.0003104544,0.00007497423,0.0003449814,0.00006421977,0.0002434218,0.0007164967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000917682,"about_ca_system_score_gemma":0.00001680241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000198912,"about_ca_topic_score_gemma":0.001012502,"domain_scores_codex":[0.9980321,0.00005823584,0.0005268194,0.0004007854,0.0003568779,0.0006251769],"domain_scores_gemma":[0.9991931,0.00003806631,0.00009393768,0.0004073859,0.00004282029,0.0002246638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002915191,0.000647735,0.03147733,0.0001010056,0.00003549502,0.00244199,0.004075405,0.000004148661,0.02457822,0.005320735,0.002887893,0.9284009],"study_design_scores_gemma":[0.2378997,0.02870105,0.211951,0.04538283,0.0008437023,0.01662506,0.01112726,0.001761806,0.3315616,0.01695367,0.08737525,0.009817082],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662933,0.0212441,0.00001863067,0.0005691758,0.0002266961,0.0005648878,0.00002587271,0.0001978241,0.01085955],"genre_scores_gemma":[0.9917235,0.004434914,0.001155988,0.0001980828,0.00007270736,0.00008957435,0.0000676061,0.00005482658,0.002202822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9185838,"threshold_uncertainty_score":0.9999483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01550490370596642,"score_gpt":0.2561935099110365,"score_spread":0.2406886062050701,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}