{"id":"W2060642773","doi":"10.1007/s11302-013-9388-x","title":"Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice","year":2013,"lang":"en","type":"article","venue":"Purinergic Signalling","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Endocrinology; Internal medicine; Adipocyte; Adipose tissue; Lipid droplet; Biology; Downregulation and upregulation; Lipid metabolism; Adipogenesis; Hyperplasia; Receptor; In vivo; Lacrimal gland; Medicine; Pathology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000200743,0.0002034988,0.0002165008,0.00008601088,0.00005458587,0.00002534561,0.0002062268,0.0001441181,0.0002748882],"category_scores_gemma":[0.00006968754,0.0002028797,0.0000997348,0.00027237,0.0000398306,0.00001810723,0.0001052975,0.0001298253,0.00009098125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003059328,"about_ca_system_score_gemma":0.00003045977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002496204,"about_ca_topic_score_gemma":0.000009972566,"domain_scores_codex":[0.9985756,0.00005893859,0.0004368692,0.0003797122,0.0001856168,0.0003632488],"domain_scores_gemma":[0.9993781,0.00002686952,0.0001230861,0.0001929401,0.0001575219,0.0001215227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001623635,0.00008800917,0.01274793,0.00003918526,0.00002814499,0.00000331014,0.00005621507,0.01665723,0.9604499,0.0001713488,0.008968833,0.0006275494],"study_design_scores_gemma":[0.001183415,0.000619168,0.009849274,0.0001334035,0.00003599264,0.00001329147,0.0001842856,0.0009904634,0.9722192,0.0001781646,0.01400134,0.0005920517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857846,0.000865556,0.01229642,0.0002033626,0.0001757839,0.0002647179,0.00001672981,0.00001961864,0.0003732082],"genre_scores_gemma":[0.9977196,0.00007510306,0.0005863928,0.0001661678,0.0005043129,0.00005733698,0.0003031656,0.00002754007,0.0005603302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01566677,"threshold_uncertainty_score":0.8273196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00791796197422432,"score_gpt":0.2187226647679054,"score_spread":0.210804702793681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}