{"id":"W2060668471","doi":"10.1002/cbic.201100567","title":"Influence of Sugar Ring Conformation on the Transportability of Nucleosides by Human Nucleoside Transporters","year":2011,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Nucleoside; Nucleoside transporter; Stereochemistry; Chemistry; Nucleoside analogue; Pyrimidine; Purine; Biochemistry; Transporter; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017106,0.0001220363,0.0001456771,0.00001773669,0.00004542417,0.000001921669,0.0002133546,0.0000970319,0.00005446997],"category_scores_gemma":[0.00001969636,0.00009674366,0.00009629046,0.00006144328,0.0001718191,0.000006448727,0.00001217314,0.00006985224,0.000001162932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004462539,"about_ca_system_score_gemma":0.00001823205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000928443,"about_ca_topic_score_gemma":0.000003297033,"domain_scores_codex":[0.999237,0.00001509948,0.0003378762,0.000166775,0.0001123983,0.0001308753],"domain_scores_gemma":[0.9993942,0.00001211839,0.0001678554,0.000312782,0.00007561807,0.0000374039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006439167,0.00007696104,0.005471176,0.00006329957,0.00003521818,3.229315e-7,0.0006926487,0.00004216924,0.992685,0.0003445291,0.0004822394,0.00004204899],"study_design_scores_gemma":[0.0002437494,0.0001376928,0.01625704,0.00003556118,0.00002204203,9.251298e-7,0.0002103684,0.000004353754,0.9826875,0.0000643496,0.0002331747,0.0001032828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969532,0.0002168227,0.00008771639,0.000025445,0.00001032384,0.0001228856,0.00002542544,0.000007878562,0.002550302],"genre_scores_gemma":[0.9996827,0.00003083713,0.00006388441,0.00009490623,0.00001753966,0.000007276024,0.00005906964,0.00001217019,0.00003167159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01078586,"threshold_uncertainty_score":0.3945092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01571079000183069,"score_gpt":0.2174402589345804,"score_spread":0.2017294689327497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}