{"id":"W2060728102","doi":"10.1042/bsr20100123","title":"IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain","year":2011,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Queen's University; Wellcome Trust","keywords":"Calmodulin; Structural motif; Myosin light-chain kinase; EF hand; Sequence motif; Chemistry; Calcium-binding protein; Binding site; Plasma protein binding; Myosin; Cell biology; Biology; Biochemistry; Calcium; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004240374,0.00008084653,0.00009944372,0.00009536818,0.00006825133,0.00001149028,0.0000346002,0.00009315075,0.000009313164],"category_scores_gemma":[0.00006481482,0.00007505208,0.00002109742,0.0001593464,0.0001366835,0.00001063466,0.00006025932,0.00003891408,1.804387e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009090958,"about_ca_system_score_gemma":0.00003572183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009507349,"about_ca_topic_score_gemma":0.00005843823,"domain_scores_codex":[0.9991786,0.00003129029,0.0002068452,0.0003356797,0.000107415,0.0001402092],"domain_scores_gemma":[0.9996307,0.000002660438,0.0001337662,0.0001346158,0.00004128504,0.00005698077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001061185,0.00004599548,0.05758123,0.00001095068,0.000002386591,0.00001041456,0.0001920374,0.000002005678,0.9414226,0.00005828724,0.00002775861,0.0006356956],"study_design_scores_gemma":[0.0001425299,0.0001371836,0.1341996,0.00001664045,0.000003993342,0.0001179966,0.00006263948,0.0001966401,0.8644556,0.00009268363,0.0004632105,0.000111263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984233,0.00007631085,0.0006085768,0.00003248966,0.0002273265,0.0001057113,0.000001106802,0.000006054174,0.0005191137],"genre_scores_gemma":[0.9994944,0.00002576132,0.0001616263,0.00001255044,0.00006092847,0.000003901728,0.000006235525,0.000005164193,0.0002294282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07696703,"threshold_uncertainty_score":0.3060535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482641092761625,"score_gpt":0.2432933092306982,"score_spread":0.228466898303082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}