{"id":"W2060728102","doi":"10.1042/bsr20100123","title":"IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain","year":2011,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Queen's University; Wellcome Trust","keywords":"Calmodulin; Structural motif; Myosin light-chain kinase; EF hand; Sequence motif; Chemistry; Calcium-binding protein; Binding site; Plasma protein binding; Myosin; Cell biology; Biology; Biochemistry; Calcium; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001194132,0.0001785702,0.0002305427,0.0001027235,0.0001144595,0.000174243,0.0002923052,0.0003143433,0.002017945],"category_scores_gemma":[0.0002124346,0.00007505478,0.0003033382,0.0001318055,0.000125279,0.0001129888,0.0001690954,0.0003706248,0.0004494922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002537411,"about_ca_system_score_gemma":0.0001342303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001305613,"about_ca_topic_score_gemma":0.001554198,"domain_scores_codex":[0.9998562,0.00001600378,0.000006236847,0.00004222314,0.00004682545,0.000032497],"domain_scores_gemma":[0.9999195,0.00001619966,0.00001494236,0.000006554039,0.00001405544,0.00002870103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001294695,0.00001653443,0.000642916,0.00002661135,0.000006237646,0.0001031527,0.00001797029,0.00009097051,0.9972377,0.0001132698,0.0001211417,0.001494143],"study_design_scores_gemma":[0.00006359596,0.000188156,0.06106386,0.00001294024,0.00003720641,0.002552382,0.00006081508,0.006346306,0.9182963,0.0003197902,0.01103939,0.00001931757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902812,0.001403289,0.005176027,0.0001387586,0.00003974316,0.00003196805,0.0005494268,0.00008891395,0.002290484],"genre_scores_gemma":[0.9947981,0.0001641579,0.002788102,0.0001253077,0.000007954888,0.00002026138,0.0007735895,0.00002050127,0.001302046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002017945,"threshold_uncertainty_score":0.006750703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01482641092761625,"score_gpt":0.2432933092306982,"score_spread":0.228466898303082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}