{"id":"W2060755230","doi":"10.1371/journal.pone.0031925","title":"Engineering of Papaya Mosaic Virus (PapMV) Nanoparticles through Fusion of the HA11 Peptide to Several Putative Surface-Exposed Sites","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immunogenicity; Epitope; Peptide; Fusion protein; Virology; Cowpea mosaic virus; Virus; Adjuvant; Antigen; Nanoparticle; Chemistry; Biology; Recombinant DNA; Plant virus; Biochemistry; Materials science; Nanotechnology; Gene; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001211367,0.0001125833,0.0001793011,0.00001190049,0.00003683536,0.000006585514,0.0001540709,0.00005674267,0.00001213725],"category_scores_gemma":[0.0001000379,0.00008274741,0.00006683523,0.0001054055,0.0000227193,0.0000146227,0.0001740786,0.00005151909,0.000006191834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008399682,"about_ca_system_score_gemma":0.00001626338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002394882,"about_ca_topic_score_gemma":0.000004007238,"domain_scores_codex":[0.9992861,0.00002349455,0.0002575033,0.00009013048,0.000144572,0.0001981717],"domain_scores_gemma":[0.9994975,0.00001622478,0.0001111522,0.0002626933,0.0000721918,0.00004025757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004006724,0.0003057361,0.005714642,0.00009629468,0.0001227794,3.336727e-8,0.001268974,0.001030833,0.9912342,0.00003755455,0.0001132478,0.00003560557],"study_design_scores_gemma":[0.0002358786,0.0001427558,0.006851083,0.00005064767,0.00004825155,7.858084e-7,0.0002210454,0.000876036,0.9912702,0.00001015106,0.0001890464,0.0001041175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989336,0.0004415989,0.0001251175,0.00006960418,0.00002444629,0.0002270507,0.00004799615,0.000006014835,0.0001246209],"genre_scores_gemma":[0.9910805,0.0000632621,0.008589601,0.00005780437,0.00003784496,0.000007771261,0.00003650779,0.00001438597,0.0001123649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008464484,"threshold_uncertainty_score":0.3374342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03399735943310058,"score_gpt":0.2154954581002745,"score_spread":0.181498098667174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}