{"id":"W2060758377","doi":"10.1186/cc14008","title":"Thalidomide exerts protective immunomodulatory action during Klebsiella pneumoniae B5055-induced acute lung infection in BALB/c mice","year":2014,"lang":"en","type":"article","venue":"Critical Care","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Children's Health Foundation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina; Financiadora de Estudos e Projetos; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Japan Society for the Promotion of Science; Russian Foundation for Basic Research; London Health Sciences Centre","keywords":"Medicine; Klebsiella pneumoniae; Thalidomide; BALB/c; Lung; Immunology; Pharmacology; Immune system; Internal medicine; Escherichia coli","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002137838,0.000470168,0.0003528977,0.0004244812,0.0002158457,0.0002116013,0.0002853604,0.0004398083,0.001070819],"category_scores_gemma":[0.0001020098,0.0001897196,0.0002905495,0.0001411396,0.0003477202,0.0003630075,0.0001351768,0.0008721598,0.0002461235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000252287,"about_ca_system_score_gemma":0.000258323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267526,"about_ca_topic_score_gemma":0.001793322,"domain_scores_codex":[0.999785,0.00003942325,0.00002193987,0.00003733558,0.00003383556,0.00008252572],"domain_scores_gemma":[0.9998704,0.00001028477,0.00004019952,0.00001075036,0.00001098819,0.00005736375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001383602,0.0003401306,0.0003825729,0.00007403694,0.000008496342,0.0001018987,0.00004781863,0.00005471803,0.9957956,0.000067351,0.0000486876,0.001695096],"study_design_scores_gemma":[0.0002305302,0.008163003,0.01905341,0.00002945719,0.00007543214,0.0004273933,0.0001259436,0.0008537729,0.969434,0.00007696019,0.001512801,0.00001730988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963954,0.001838913,0.0004938772,0.000112184,0.00002969529,0.00003248703,0.0002198303,0.00004854644,0.0008290389],"genre_scores_gemma":[0.9961747,0.001040544,0.0009192768,0.00007040785,0.00001665861,0.00003725661,0.0002298172,0.000007509984,0.001503888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001267526,"threshold_uncertainty_score":0.003582299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02629961850150677,"score_gpt":0.3577494663135856,"score_spread":0.3314498478120789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}