{"id":"W2060759590","doi":"10.1007/s10048-014-0403-3","title":"Genetic variants in IL2RA and IL7R affect multiple sclerosis disease risk and progression","year":2014,"lang":"en","type":"article","venue":"Neurogenetics","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canada Excellence Research Chairs, Government of Canada; Canada Research Chairs","keywords":"Disease; Odds ratio; Multiple sclerosis; Family history; Genetic association; Medicine; Internal medicine; Genotyping; Biology; Oncology; Genetics; Genotype; Immunology; Single-nucleotide polymorphism; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001074712,0.0008845714,0.0005392442,0.001441687,0.0005153698,0.0009684017,0.0006741909,0.001346126,0.00322245],"category_scores_gemma":[0.003545039,0.0003617748,0.001052479,0.001193166,0.000453993,0.0006193541,0.0004993568,0.0007649146,0.0004647071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001949683,"about_ca_system_score_gemma":0.000253407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002698581,"about_ca_topic_score_gemma":0.001782509,"domain_scores_codex":[0.998908,0.0004966752,0.0001106277,0.0002244488,0.0001408371,0.0001192928],"domain_scores_gemma":[0.9977175,0.0009160709,0.0007493828,0.0001968674,0.0002164369,0.000203739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002793777,0.0002439651,0.9748694,0.00004939408,0.001234051,0.001487335,0.0005460071,0.0001930284,0.01177981,0.000252457,0.0003194218,0.006231347],"study_design_scores_gemma":[0.00008860405,0.0003115165,0.9938557,0.00003228054,0.0006068299,0.0019576,0.0003135552,0.0004030316,0.001491049,0.0003644756,0.0005603197,0.00001510473],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980375,0.0006667448,0.0002357132,0.00009460372,0.00001410451,0.0000047006,0.0001627311,0.00001373471,0.0007701001],"genre_scores_gemma":[0.9985885,0.0001848737,0.0002596007,0.00004646019,0.0000266089,0.000006992721,0.000201565,0.0000127932,0.0006724112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00322245,"threshold_uncertainty_score":0.0107801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04362144759612199,"score_gpt":0.2994016019063366,"score_spread":0.2557801543102146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}