{"id":"W2060800255","doi":"10.1016/s0264-410x(00)00208-5","title":"Oral, intrarectal and intranasal immunizations using CpG and non-CpG oligodeoxynucleotides as adjuvants","year":2000,"lang":"en","type":"article","venue":"Vaccine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":158,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"","keywords":"CpG Oligodeoxynucleotide; Adjuvant; Nasal administration; Toxoid; Immune system; Antigen; Immunology; Medicine; CpG site; Tetanus; Immunization; Antibody; Vaccination; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001366417,0.0001513242,0.0002259978,0.0001216414,0.0002844848,0.00003227131,0.00008178504,0.0001519155,0.002494227],"category_scores_gemma":[0.00004095924,0.0001375444,0.00002560336,0.0001507545,0.00004313903,0.0002519827,0.00004569596,0.0001633944,0.0001772849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001430273,"about_ca_system_score_gemma":0.0000347886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000304011,"about_ca_topic_score_gemma":0.0000296535,"domain_scores_codex":[0.9992027,0.0001054243,0.0002487749,0.0001892609,0.00002039636,0.000233397],"domain_scores_gemma":[0.9996509,0.00006177573,0.00005073435,0.0001725847,0.00004135918,0.0000226637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009485574,0.00009420762,0.004776559,0.00002930939,0.0002539825,0.00001345785,0.001150025,0.00005419228,0.8930683,0.0005701487,0.001919448,0.09712179],"study_design_scores_gemma":[0.01108734,0.0011398,0.2681318,0.000320939,0.0004061307,0.001848825,0.0009434246,0.002096611,0.6405651,0.00127049,0.07097169,0.001217827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959976,0.002493754,0.00016915,0.0003510049,0.0001379874,0.0001596041,0.000007229531,0.00005008033,0.0006335978],"genre_scores_gemma":[0.9971218,0.001417658,0.0001646887,0.0001232633,0.00003000101,0.000008343521,0.00006356285,0.00001819766,0.001052513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2633552,"threshold_uncertainty_score":0.9984176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006817715667961458,"score_gpt":0.2337058887350081,"score_spread":0.2268881730670466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}