{"id":"W2060803241","doi":"10.1016/j.micinf.2013.05.001","title":"The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection","year":2013,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Citrobacter rodentium; Enteropathogenic Escherichia coli; Biology; Virulence; Microbiology; Intimin; Type three secretion system; Effector; Secretion; Enterobacteriaceae; Tight junction; Citrobacter; Shigella; Escherichia coli; Pathogen; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002014337,0.000128956,0.0001109763,0.00004521806,0.0003519679,0.00008280754,0.00002075372,0.00008483313,0.000005473503],"category_scores_gemma":[0.00006762983,0.0001010503,0.00006717794,0.00007170195,0.0001096931,0.00003074828,0.00007267833,0.00008431652,8.568128e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002572466,"about_ca_system_score_gemma":0.00001540431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002566722,"about_ca_topic_score_gemma":0.0002508466,"domain_scores_codex":[0.999219,0.00005249478,0.0002461058,0.000236029,0.00006537876,0.0001810009],"domain_scores_gemma":[0.999533,0.00001596905,0.0001460013,0.00009444961,0.0001739354,0.00003663398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000929887,0.00003744836,0.0568176,0.00009509194,0.0000388186,8.698412e-8,0.00006788498,0.000004168155,0.9404508,0.00001408943,0.0001400435,0.002240965],"study_design_scores_gemma":[0.0007514918,0.0005745734,0.4164763,0.00005668085,0.00004041953,0.00002380709,0.00004969924,0.0005858635,0.5789224,0.00006789216,0.002309483,0.0001413678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960619,0.0004128516,0.002724797,0.00009005779,0.0001877161,0.0004844402,0.000007830542,0.000013398,0.00001702353],"genre_scores_gemma":[0.9962865,0.003092691,0.0001194925,0.00002829975,0.0001890906,0.0001297745,0.0000330831,0.00001425357,0.0001068885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3615284,"threshold_uncertainty_score":0.412071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006442805561791919,"score_gpt":0.2322643487977744,"score_spread":0.2258215432359825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}