{"id":"W2060812669","doi":"10.1007/s004250100582","title":"Berberine bridge enzyme, a key branch-point enzyme in benzylisoquinoline alkaloid biosynthesis, contains a vacuolar sorting determinant","year":2001,"lang":"en","type":"article","venue":"Planta","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; McKnight Foundation","keywords":"Sanguinarine; Biochemistry; Signal peptide; Biology; Benzylisoquinoline; Vacuole; Biosynthesis; Peptide sequence; Enzyme; Molecular biology; Gene; Alkaloid; Cytoplasm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001534513,0.0004580528,0.0007432193,0.000174876,0.0002845673,0.0005727453,0.0001662869,0.0006359987,0.001684636],"category_scores_gemma":[0.0003041058,0.0002039342,0.0002691094,0.0001792382,0.0002538702,0.0007015333,0.0002840252,0.0005176049,0.002211783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007013461,"about_ca_system_score_gemma":0.0002339189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007217288,"about_ca_topic_score_gemma":0.001328464,"domain_scores_codex":[0.9998957,0.00001263424,0.00000781637,0.00003791022,0.00002641472,0.00001940272],"domain_scores_gemma":[0.9997008,0.00008082807,0.00006680432,0.00003600079,0.00003942643,0.00007611619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001554253,0.00001091681,0.0002467442,0.00003777991,0.000003842336,0.0001159457,0.00002534336,0.00003316102,0.9959466,0.0002677111,0.000103292,0.003053244],"study_design_scores_gemma":[0.00001822341,0.00008799523,0.006303987,0.000005774746,0.0000129167,0.0007914588,0.00002889227,0.0007358562,0.9859983,0.000183854,0.005820788,0.00001202655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679355,0.004010408,0.02337052,0.000278512,0.00008324253,0.00003054272,0.000596523,0.000709734,0.002985089],"genre_scores_gemma":[0.9765154,0.001161385,0.0110089,0.0001403154,0.00003595765,0.00001832293,0.002659112,0.0001597588,0.008300861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001684636,"threshold_uncertainty_score":0.005635679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03231901658215773,"score_gpt":0.3010304587445399,"score_spread":0.2687114421623822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}