{"id":"W2060818486","doi":"10.1074/jbc.m111.305268","title":"Cell-Cell Membrane Fusion Induced by p15 Fusion-associated Small Transmembrane (FAST) Protein Requires a Novel Fusion Peptide Motif Containing a Myristoylated Polyproline Type II Helix","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Polyproline helix; Ectodomain; Transmembrane domain; Lipid bilayer fusion; Peptide; Myristoylation; Chemistry; Biophysics; Chinese hamster ovary cell; Transmembrane protein; Peptide sequence; Liposome; Cell membrane; Lipid bilayer; Amino acid; Protein structure; Biochemistry; Membrane; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002290002,0.0002725594,0.0001803338,0.0001048759,0.0001134393,0.0002460362,0.0001296818,0.0002449782,0.0003787903],"category_scores_gemma":[0.0002203949,0.0001118362,0.0002730018,0.0001033077,0.0002071078,0.0002598991,0.0002538888,0.0003133391,0.0001620962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003420349,"about_ca_system_score_gemma":0.0001770302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002427417,"about_ca_topic_score_gemma":0.0002731466,"domain_scores_codex":[0.9998444,0.00003661925,0.00001956349,0.00002742899,0.00003736181,0.00003459768],"domain_scores_gemma":[0.9998659,0.0000464437,0.00003769812,0.00001245022,0.00001257698,0.00002487738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004253882,0.000006101682,0.00007267336,0.00001101035,0.000001666523,0.00003192099,0.000006335652,0.00004580187,0.9994266,0.00009206094,0.00000486238,0.0002584746],"study_design_scores_gemma":[0.000009445404,0.0001788675,0.001515669,0.000002630775,0.000004420888,0.0001767451,0.000009273754,0.0008907028,0.9967669,0.00004033167,0.0004025578,0.000002566603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966789,0.0002549865,0.002540888,0.00002027637,0.000006013706,0.00002012802,0.00007042844,0.00002381981,0.0003844458],"genre_scores_gemma":[0.9971481,0.0001505186,0.002129253,0.00001792989,0.000003326023,0.0000173354,0.0001626846,0.000006635077,0.0003641732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003787903,"threshold_uncertainty_score":0.002481699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03349639384070259,"score_gpt":0.230661869467738,"score_spread":0.1971654756270353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}