{"id":"W2060895401","doi":"10.1038/onc.2009.381","title":"Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling","year":2009,"lang":"en","type":"article","venue":"Oncogene","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health","keywords":"Biology; Comparative genomic hybridization; Gene expression profiling; Immunohistochemistry; Gene expression; Molecular biology; Cancer research; Gene; Pathology; Genetics; Immunology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008645004,0.0002063184,0.0005565717,0.001694566,0.0003487088,0.000798993,0.0004268983,0.0002274644,0.001265592],"category_scores_gemma":[0.0008018237,0.0002127461,0.0003327727,0.0007485147,0.0002657272,0.0006123199,0.0004931319,0.0005690451,0.0002911235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003727663,"about_ca_system_score_gemma":0.0003229127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001118896,"about_ca_topic_score_gemma":0.002551266,"domain_scores_codex":[0.9997037,0.00005196756,0.00002552215,0.00006693372,0.00009289681,0.00005890999],"domain_scores_gemma":[0.999711,0.00009544057,0.00006506483,0.00004498982,0.00005569081,0.00002779461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009802628,0.0001497188,0.1381528,0.0001629767,0.0001559525,0.0004097203,0.0004181134,0.001206833,0.7618284,0.001699922,0.0004217591,0.09441367],"study_design_scores_gemma":[0.0001472953,0.001035496,0.4738069,0.0000713773,0.001160893,0.005819304,0.002032186,0.02495462,0.4686515,0.004846101,0.01742143,0.00005291154],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815833,0.001749596,0.0119425,0.0002555018,0.00001228234,0.00009482506,0.000605488,0.0001118223,0.003644602],"genre_scores_gemma":[0.9856569,0.0007000412,0.01170659,0.00006086827,0.00001231102,0.00005373743,0.0008721111,0.00002744404,0.000910082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001694566,"threshold_uncertainty_score":0.004571974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01628649804611494,"score_gpt":0.3000180457273089,"score_spread":0.283731547681194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}