{"id":"W2060927440","doi":"10.1159/000211339","title":"Inhibition of Cytokine Gene Expression in Mouse Skin by Subcutaneous Injection of Cyclosporine","year":2009,"lang":"en","type":"article","venue":"Skin Pharmacology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cytokine; Gene expression; In vivo; Tumor necrosis factor alpha; Biology; Subcutaneous injection; Pharmacology; Interleukin; Molecular biology; Immunology; Gene; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002862329,0.0007368055,0.0003502714,0.0006868744,0.0002023574,0.0003395563,0.0002564151,0.000345404,0.001477872],"category_scores_gemma":[0.0001124914,0.0002684744,0.0003978126,0.0003594917,0.0004446943,0.0002764777,0.0001229716,0.001260331,0.0006203052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002811093,"about_ca_system_score_gemma":0.0003423587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003513823,"about_ca_topic_score_gemma":0.0006386738,"domain_scores_codex":[0.9997099,0.00004709297,0.00002988117,0.00006757772,0.00007675793,0.00006877191],"domain_scores_gemma":[0.9997336,0.00005342243,0.00008575714,0.00004724596,0.00002103502,0.00005884959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001290465,0.00006035951,0.00006018627,0.00002068621,0.000002594007,0.00002027929,0.000008098936,0.00002744618,0.9989629,0.00003558126,0.00001471157,0.0006580867],"study_design_scores_gemma":[0.00002981672,0.0008020919,0.0009588373,0.00000665346,0.00001297212,0.00008957202,0.00001078261,0.000249314,0.9971731,0.00002393238,0.0006406178,0.000002338245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835925,0.003320742,0.007837478,0.0001988029,0.0001121407,0.000169816,0.0009998856,0.0004697328,0.003298954],"genre_scores_gemma":[0.976476,0.0044676,0.009149984,0.0001204704,0.00005759361,0.0003074154,0.001115979,0.0001058223,0.008199086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001477872,"threshold_uncertainty_score":0.004943967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006358844078557961,"score_gpt":0.2572151002069418,"score_spread":0.2508562561283838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}